Filters

PRMT6 Antibody

PRMT6 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePRMT6 Primary Polyclonal Antibody
Also known asPRMT6 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPRMT6
SpecificityThis is a highly specific antibody against PRMT6
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range330-375/375
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PRMT6
Gene ID number55170
Swiss ProtQ96LA8
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts as a regulator of DNA base excision during DNA repair by mediating the methylation of DNA polymerase beta (POLB), Acts as a transcriptional coactivator of a number of steroid hormone receptors including ESR1, Acts as a transcriptional repressor of various genes such as HOXA2, Also methylates histone H2A and H4 'Arg-3' (H2AR3me and H4R3me, ESR2, H3R2me2a represents a specific tag for epigenetic transcriptional repression and is mutually exclusive with methylation on histone H3 'Lys-4' (H3K4me2 and H3K4me3), May play a role in innate immunity against HIV-1 in case of infection by methylating and impairing the function of various HIV-1 proteins such as Tat, Methylates HMGA1, PGR and NR3C1, Preferentially methylates arginyl residues present in a glycine and arginine-rich domain and displays preference for monomethylated substrates, Promotes fasting-induced transcriptional activation of the gluconeogenic program through methylation of the CRTC2 transcription coactivator, Regulates alternative splicing events, Repression of TP53 blocks cellular senescence (By similarity), Rev and Nucleocapsid protein p7 (NC), Specifically mediates the asymmetric dimethylation of histone H3 'Arg-2' to form H3R2me2a, THBS1 and TP53, leading to the stimulation of its polymerase activity by enhancing DNA binding and processivity, respectively), with a strong preference for the formation of aDMA, Arginine methyltransferase that can catalyze the formation of both omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6, Histone-arginine N-methyltransferase PRMT6, PRMT6, Protein arginine N-methyltransferase 6, HRMT1L6
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPRMT6
Short namePRMT6 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePRMT6 (Antibody to)
Alternative techniqueantibodies
Identity 18241
Gene PRMT6
Long gene name protein arginine methyltransferase 6
Synonyms gene HRMT1L6
Synonyms gene name HMT1 hnRNP methyltransferase-like 6 (S, cerevisiae)
Synonyms FLJ10559
Locus 1p13, 3
Discovery year 2004-06-22
GenBank acession AK001421
Entrez gene record 55170
Pubmed identfication 11724789
RefSeq identity NM_018137
Classification Protein arginine methyltransferases
Havana BLAST/BLAT OTTHUMG00000010964

Similar products

Subscribe to our Newsletter