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Progesterone Receptor(Ser190) Antibody

Progesterone Receptor(Ser190) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameProgesterone Receptor(Ser190) Antibody
Also known asProgesterone Receptor(Ser190) Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenProgesterone Receptor Ser190
SpecificityThis is a highly specific antibody against Progesterone Receptor Ser190
Modification(s)Phosphorylation
Modification site(s)Ser190
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from rat Progesterone Receptor around the phosphorylation site of Ser190
Gene ID number5241
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Rat, Mouse
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen ER alpha and ER beta, ER alpha and ER beta have been shown to be differentially activated by various ligands, In most cells, The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor (hPR-Aand hPR-B), The carboxy terminal region of the estrgen receptor contains the ligand binding domain, The interaction of hormone-bound estrogen receptors with estrogen responsive elements(EREs) alters transcription of ERE-containing genes, Two forms of estrogen receptor have been identified, and the DNA binding domain is centrally located, hPR-B functions as a transcriptional activator of progesterone-responsive gene, the amino terminus serves as the transactivation domain, whereas hPR-A function as a transcriptional inhibitor of all steroid hormone receptors, which arise from alternative splicing, Estrogen and progesterone receptor are members of a family of transcription factors that are regulated by the binding of their cognate ligands
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names NR3C3, Nuclear receptor subfamily 3 group C member 3, PGR, PR, PRA, PRB, PRGR_RAT, Progesterone receptor, Progestin receptor form A, Progestin receptor form B, PGRphospho S190
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetProgesterone Receptor(Ser190)
Short nameProgesterone Receptor(Ser190) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameProgesterone Receptor(Ser190) (Antibody to)
Alternative techniqueantibodies

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