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Prominin 2 Antibody

Prominin 2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameProminin 2 Primary Polyclonal Antibody
Also known asProminin 2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenProminin 2
SpecificityThis is a highly specific antibody against Prominin 2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range315-365/834
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Prominin 2
Gene ID number150696
Swiss ProtQ8N271
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Like Prominin 1, Prominin 2 expression is likely to be involved in growth suppression in the prostate, Similar to Prominin1 localization, and all along the digestive track and other epithelial tissues, and down-regulation of Prominin 2 may disrupt normal prostatic homeostasis and lead to uncontrolled prostatic growth, but their genomic organization is strikingly similar, suggesting a tumor suppressive role for Prominin 2, the Prominin 2 is also associated with membrane protrusions of the epithelial cells from adult kidney, the prominin 2 exhibit similar membrane topology with 5 trans-membrane domains and two large glycosylated extracellular domains, Prominin 2 expression is down-regulated in aggressive prostate cancer cell lines and transient transfection of PROML2 expression vectors has been shown to induce apoptosis in cultured prostate cancer cells, Prominin 2 is a 112 kDa glycoporotein structurally related to Prominin 1 (CD133) although amino acid similarity is not more than 30%
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names PROM-2, PROM2, Prominin-2, Prominin-like protein 2, UNQ2521/PRO6014, hPROML2, PROML2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetProminin 2
Short nameProminin 2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameProminin 2 (Antibody to)
Alternative techniqueantibodies
Identity 20685
Gene PROM2
Long gene name prominin 2
Locus 2q11, 1
Discovery year 2003-03-25
GenBank acession AF245303
Entrez gene record 150696
Pubmed identfication 12514187
RefSeq identity NM_144707
Havana BLAST/BLAT OTTHUMG00000130393

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