Prominin 2 Antibody, Biotin Conjugated

Prominin 2 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 333

Size 0.1ml

Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit

Long name	Biotin Conjugated, Prominin 2 Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Biotinylated
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	Prominin 2
Specificity	This is a highly specific antibody against Prominin 2
Modification	Unmodified
Modification site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Immunogen_range	315-365/834
Subcellular location	Extracellular
Source	KLH conjugated synthetic peptide derived from human Prominin 2
Gene ID number	150696
Swiss Prot	Q8N271
Tested applications	IHC-P, WB
Recommended dilutions	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity	Mouse, Rat, Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	Like Prominin 1, Prominin 2 expression is likely to be involved in growth suppression in the prostate, Similar to Prominin1 localization, and all along the digestive track and other epithelial tissues, and down-regulation of Prominin 2 may disrupt normal prostatic homeostasis and lead to uncontrolled prostatic growth, but their genomic organization is strikingly similar, suggesting a tumor suppressive role for Prominin 2, the Prominin 2 is also associated with membrane protrusions of the epithelial cells from adult kidney, the prominin 2 exhibit similar membrane topology with 5 trans-membrane domains and two large glycosylated extracellular domains, Prominin 2 expression is down-regulated in aggressive prostate cancer cell lines and transient transfection of PROML2 expression vectors has been shown to induce apoptosis in cultured prostate cancer cells, Prominin 2 is a 112 kDa glycoporotein structurally related to Prominin 1 (CD133) although amino acid similarity is not more than 30%
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	N/A
Synonyms	PROM-2, PROM2, Prominin-2, Prominin-like protein 2, UNQ2521/PRO6014, hPROML2, PROML2
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	Prominin 2 Conjugated
Short name	Conjugated, Prominin 2 Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Biotin
Alternative name	biotinilated coupled, Prominin 2 (Antibody to)
Alternative technique	antibodies

Prominin 2 Antibody, Biotin Conjugated

Prominin 2 Antibody, Biotin Conjugated size: 0.1ml 333

Similar products

Subscribe to our Newsletter