Name : ProSAPiP1 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN8502076844
| Long name | ProSAPiP1 Primary Polyclonal Antibody |
| Also known as | ProSAPiP1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | ProSAPiP1 |
| Specificity | This is a highly specific antibody against ProSAPiP1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 180-230/673 |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ProSAPiP1 |
| Gene ID number | 9762 |
| Swiss Prot | O60299 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | ProSAPiP1 (proline rich synapse associated protein interacting protein 1) is a 673 amino acid protein that interacts with the PDZ domain of Shank 3, ProSAPiP1 expression is brain-specific with highest expression within the cerebellum, Shank proteins contain PDZ modular domains that coordinate the synaptic localization of ion channels, The PDZ domain mediates protein-protein interactions via the recognition of a conserved sequence motif at the C-terminus of their target protein(s), The PSD is an electron-dense structure underneath the post-synaptic plasma membrane of excitatory synapses that anchors and clusters glutamate receptors opposite to the pre-synaptic neurotransmitter release site, and cell adhesion molecules, hippocampus and cerebral cortex, receptors, signaling enzymes, The ProSAP family of proteins contain many protein-protein interaction domains and serve as scaffolding mediators within the post-synaptic density (PSD) of excitatory brain synapses |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | KIAA0552, LZTS3, Leucine zipper putative tumor suppressor 3, ProSAP-interacting protein 1, PROSAPIP1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ProSAPiP1 |
| Short name | ProSAPiP1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | ProSAPiP1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 30139 |
| Gene | LZTS3 |
| Long gene name | leucine zipper tumor suppressor family member 3 |
| Synonyms | ProSAPiP1 KIAA0552 |
| Synonyms name | ProSAP/Shank-interacting protein 1 |
| Locus | 20p13 |
| Discovery year | 2016-07-08 |
| Entrez gene record | 9762 |
| Pubmed identfication | 16012743 16522626 |
| RefSeq identity | NM_014731 |
| Classification | Leucine zipper tumor suppressor family |