| Alternative name1 | EC 2, EIF2AK1, EIF2AK2, Interferon-Inducible Double Stranded RNA-Activated Protein Kinase (PRKR, MGC126524), 1, 7, 11, Anti-Protein Kinase |
| Alternative name2 | EC 2, EIF2AK1, EIF2AK2, Interferon-Inducible Double Stranded RNA-Activated Protein Kinase (PRKR, MGC126524), 1, 7, 11, Protein Kinase |
| Alternative name3 | EC 2, EIF2AK1, EIF2AK2, Interferon-Inducible Double Stranded RNA-Activated Protein Kinase (PRKR, MGC126524), 1, 7, 11, Protein Kinase |
| Alternative name4 | Interferon-Inducible Double Stranded RNA-Activated Protein Kinase, Protein Kinase |
| Alternative name5 | EC 2, EIF2AK1, EIF2AK2, Interferon-Inducible Double Stranded RNA-Activated Protein Kinase (PRKR, MGC126524), 1, 7, 11, Anti -Protein Kinase |
| Other names | N/A |
| Gene name | N/A |
| Gene name synonims | N/A |
| Other gene names | N/A |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | N/A |
| Clone | Polyclonal antibody |
| Host organism | Source: Human, Host: Rabbit |
| Species reactivity | Human |
| Specificity and cross-reactivity | Mouse, Rat, Species Crossreactivity: Human, Recognizes Human Interferon-Induced Double-Stranded RNA-Activated Protein Kinase (PRKR) (EIF2AK2) |
| Purification method | N/A |
| Form/Appearance | 0, 02% sodium azide, Supplied as a liquid in PBS |
| Concentration | N/A |
| Storage and shipping | Aliquots are stable for at least 3 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, aliquot and For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for: | Immunohistochemistry (IHC), Western Blot (WB) |
| Description | Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target | EC 2, EIF2AK1, EIF2AK2, Interferon Double Stranded RNA-Activated Protein Kinase (PRKR, MGC126524), 1, 7, 11, Protein Kinase |
| Short name | EC 2, EIF2AK1, EIF2AK2, Interferon- Double Stranded RNA-Activated Protein Kinase (PRKR, MGC126524) Antibody, 1, 7, 11, Protein Kinase |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | EC 2, EIF2AK1, Interferon-Inducible Double Stranded RNA-Activated Protein phosphorylation catalyst (PRKR, MGC126524) (Antibody to), eukaryotic translation initiation factor 2-a phosphorylation catalyst 2, 1, 7, 11, Protein phosphorylation catalyst |
| Alternative technique | antibodies |
| Alternative to gene target | DNA-templated and biological process this GO :0006412 and translation and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008601 and protein phosphatase type 2A regulator activity and molecular function this GO :0009615 and response to virus and biological process this GO :0016020 and membrane and cellular component this GO :0016772 and transferase activity, EIF2AK1 and PKR and PPP1R83 and PRKR, EIF2AK2 and IDBG-44867 and ENSG00000055332 and 5610, EIF2AK2 and IDBG-632472 and ENSBTAG00000008703 and 347700, Eif2ak2 and IDBG-199014 and ENSMUSG00000024079 and 19106, nuclei, this GO :0000186 and activation of MAPKK activity and biological process this GO :0001819 and positive regulation of cytokine production and biological process this GO :0003725 and double-stranded RNA binding and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004694 and eukaryotic translation initiation factor 2alpha kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004715 and non-membrane spanning protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0003725: double-stranded RNA binding, this GO :0003725: double-stranded RNA binding and also this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004694: eukaryotic translation initiation factor 2alpha kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0004715: non-membrane spanning protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0008601: protein phosphatase type 2A regulator activity and also this GO :0016772: transferase activity, this GO :0004672: protein kinase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004694: eukaryotic translation initiation factor 2alpha kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004715: non-membrane spanning protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0008601: protein phosphatase type 2A regulator activity, this GO :0016772: transferase activity, this GO :0044822: poly(A) RNA binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0044822: poly(A) RNA binding, transferring phosphorus-containing groups and molecular function this GO :0017148 and negative regulation of translation and biological process this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019048 and modulation by virus of host morphology or physiology and biological process this GO :0019054 and modulation by virus of host process and biological process this GO :0019058 and viral life cycle and biological process this GO :0030683 and evasion or tolerance by virus of host immune response and biological process this GO :0030968 and endoplasmic reticulum unfolded protein response and biological process this GO :0032722 and positive regulation of chemokine production and biological process this GO :0032874 and positive regulation of stress-activated MAPK cascade and biological process this GO :0033689 and negative regulation of osteoblast proliferation and biological process this GO :0035455 and response to interferon-alpha and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045071 and negative regulation of viral genome replication and biological process this GO :0045087 and innate immune response and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051607 and defense response to virus and biological process this GO :1900225 and regulation of NLRP3 inflammasome complex assembly and biological process this GO :1901224 and positive regulation of NIK/NF-kappaB signaling and biological process this GO :1901532 and regulation of hematopoietic progenitor cell differentiation and biological process this GO :1902033 and regulation of hematopoietic stem cell proliferation and biological process this GO :1902036 and regulation of hematopoietic stem cell differentiation and biological process, eukaryotic translation initiation factor 2-alpha kinase 2 |
| Identity | 9437 |
| Gene | EIF2AK2 |
| Long gene name | eukaryotic translation initiation factor 2 alpha kinase 2 |
| Synonyms gene | PRKR |
| Synonyms gene name | interferon-inducible double stranded RNA dependent , protein kinase |
| Synonyms | PKR EIF2AK1 PPP1R83 |
| Synonyms name | protein phosphatase 1, regulatory subunit 83 |
| Locus | 2p22, 2 |
| Discovery year | 1992-12-04 |
| GenBank acession | BC057805 |
| Entrez gene record | 5610 |
| Pubmed identfication | 1351683 |
| RefSeq identity | NM_002759 |
| Classification | Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT | OTTHUMG00000100962 |
Technique
Supplier
Species
Label
Iso Type
Host
Tissue