Name : PSAP Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN2273903533
| Long name | Cy3 Conjugated, PSAP Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | PSAP/PAP |
| Specificity | This is a highly specific antibody against PSAP/PAP |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 144-194/524 |
| Subcellular location | Secreted |
| Source | KLH conjugated synthetic peptide derived from human PSAP |
| Gene ID number | 5660 |
| Swiss Prot | P07602 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | GM1 gangliosides by beta-galactosidase (EC 3, GPR37 and GPR37L1, Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, Saposin-B forms a solubilizing complex with the substrates of the sphingolipid hydrolases, Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A (EC 3, Saposin-C apparently acts by combining with the enzyme and acidic lipid to form an activated complex, Saposin-D is a specific sphingomyelin phosphodiesterase activator (EC 3, Saposins are specific low-molecular mass non-enzymic proteins, rather than by solubilizing the substrate, these effects are mediated by its G-protein-coupled receptors, they participate in the lysosomal degradation of sphingolipids, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling, which takes place by the sequential action of specific hydrolases, 1, 1, 1, 1, 1, 1, 12), 2, 2, 2, 2, 22), 23) and globotriaosylceramide by alpha-galactosidase A (EC 3, 4, 45) and galactosylceramide by beta-galactosylceramidase (EC 3, 46), 6, 8), Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase (EC 3 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Properties | 1 of the PSAP Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | PSAP Conjugated |
| Short name | Conjugated, PSAP Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | cyanine 3 coupled, PSAP (Antibody to) |
| Alternative technique | antibodies |
| Identity | 9498 |
| Gene | PSAP |
| Long gene name | prosaposin |
| Synonyms gene | SAP1 GLBA |
| Synonyms gene name | sphingolipid activator protein-1 |
| Synonyms name | variant Gaucher disease and variant metachromatic leukodystrophy |
| Locus | 10q22, 1 |
| Discovery year | 1986-01-01 |
| GenBank acession | BC004275 |
| Entrez gene record | 5660 |
| Pubmed identfication | 2717620 |
| RefSeq identity | NM_002778 |
| Classification | Endogenous ligands |
| Havana BLAST/BLAT | OTTHUMG00000018429 |