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PSCDBP/CYTIP Antibody

PSCDBP/CYTIP Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePSCDBP/CYTIP Primary Polyclonal Antibody
Also known asPSCDBP/CYTIP PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPSCDBP/CYTIP
SpecificityThis is a highly specific antibody against PSCDBP/CYTIP
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PSCDBP/CYTIP
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Additionally, After membrane translocation, CYTIP associates with SNX27 (sorting nexin 27) and helps to coordinate trafficking and signaling complexes, CYTIP can be re-located to the cytoplasm via exposure to a phorbol ester, CYTIP can be recruited from the cytoplasm to the membrane by leukocyte integrins which interact with CYTIP through its PDZ domain, CYTIP is able to sequester it to the cytoplasm, CYTIP regulates the activity of cytohesin-1 (an integrin-activating protein involved in cell adhesion) by mediating its recruitment to the leukocyte membrane, Expressed primarily in hematopoetic cells, Through its ability to bind cytohesin-1, Up-regulation of CYTIP is observed in maturing dendritic cells, suggesting a possible role in developmentally-controlled cell adhesion, thereby preventing cytohesin-1 translocation to lymphocytes and interrupting the flow of information in the cell adhesion pathway, CYTIP is a cytoplasmic protein that is involved in lymphocytic cell adhesion
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CASP, CYBR, CYTHIP, CYTIP_HUMAN, Cbp HE, Cytip, Cytohesin binder and regulator, Cytohesin-associated scaffolding protein, Cytohesin-binding protein HE, Cytohesin-interacting protein, HE antibody Pleckstrin Homology Sec7 and Coiled-Coil Domains Binding Protein, Pleckstrin homology Sec7 and coiled-coil domains-binding protein, B31
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPSCDBP/CYTIP
Short namePSCDBP/CYTIP Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePSCDBP/cytohesin 1 interacting protein (Antibody to)
Alternative techniqueantibodies
Alternative to gene target B3-1 and CASP and CYBR and CYTHIP and HE and PSCDBP, CYTIP and IDBG-641611 and ENSBTAG00000008329 and 540450, CYTIP and IDBG-72874 and ENSG00000115165 and 9595, Cytip and IDBG-171958 and ENSMUSG00000026832 and 227929, nuclei, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005769 and early endosome and cellular component this GO :0005938 and cell cortex and cellular component this GO :0030155 and regulation of cell adhesion and biological process this GO :0045087 and innate immune response and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, cytohesin 1 interacting protein
Identity 9506
Gene CYTIP
Long gene name cytohesin 1 interacting protein
Synonyms gene PSCDBP
Synonyms gene name Sec7 and coiled-coil domains, binding protein , pleckstrin homology
Synonyms B3-1 HE CYBR CASP CYTHIP
Synonyms name cytohesin binding protein HE cytohesin binder and regulator
Locus 2q24, 1
Discovery year 1999-07-19
GenBank acession L06633
Entrez gene record 9595
Pubmed identfication 18926288 10343115 11867758 20530790 21562043
RefSeq identity NM_004288
Classification PDZ domain containing
Havana BLAST/BLAT OTTHUMG00000154551

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