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PSD-95 Antibody (PSD95)

PSD-95 Antibody (PSD95) size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenPSD-95 (PSD95)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0
Notes Titration of the PSD-95 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis PSD-95 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P78352
PurityAntigen affinity
Description DLG2, DLG4 can heteromultimerize with another MAGUK protein, DLG4 can orchestrate synaptic development and it has a role in synapse stabilization and plasticity, It is a member of the membrane-associated guanylate kinase (MAGUK) family, Overexpression of DLG4 in hippocampal neurons could drive maturation of glutamatergic synapses, These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, Ubiquitination of DLG4 through an MDM2-mediated pathway can regulate AMPA receptor surface expression during synaptic plasticity, also known as Post-synaptic density protein 95 (PSD-95) or SAP-90, and associated signaling proteins, and is recruited into NMDA receptor and potassium channel clusters, ion channels, is a protein that in humans is encoded by the DLG4 gene, DLG4 (Discs large homolog 4)
Immunogen mouse and rat), An amino acid sequence from the C-terminus of human PSD-95 (RRVERREWSRLKAKDW) was used as the immunogen for this PSD-95 antibody (100% homologous in human
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the PSD-95 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetPSD (PSD95)
Short namePSD-95 Antibody (PSD95)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePSD-95 (Antibody to) (PSD95)
Alternative techniqueantibodies
Identity 2903
Gene DLG4
Long gene name discs large MAGUK scaffold protein 4
Synonyms gene name discs, large homolog 4 (Drosophila) discs large homolog 4
Synonyms PSD-95 PSD95 SAP90 SAP-90
Locus 17p13, 1
Discovery year 1995-11-07
GenBank acession U83192
Entrez gene record 1742
Pubmed identfication 9286702
RefSeq identity NM_001365
Classification Membrane associated guanylate kinases PDZ domain containing
Havana BLAST/BLAT OTTHUMG00000134327

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