Name : PSMA1 Antibody / Proteasome 20S alpha 1
Supplier : NJS POLY
Price :406
SKU : GEN6738998084
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | PSMA1 / Proteasome 20S alpha 1 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | IHC-P, WB |
| Recommended dilutions | 5-1ug/ml, IHC (FFPE): 1-2ug/ml, Western blot: 0 |
| Added buffer | 025% sodium azide, 5% BSA and 0, Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2 |
| Intented use | This PSMA1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P25786 |
| Purity | Antigen affinity |
| Description | 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits, Alternative splicing results in multiple transcript variants encoding distinct isoforms, An essential function of a modified proteasome, Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway, The core structure is composed of 4 rings of 28 non-identical subunits, The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure, This gene encodes a member of the peptidase T1A family, is the processing of class I MHC peptides, that is a 20S core alpha subunit, the immunoproteasome, Proteasome subunit alpha type-1 is a protein that in humans is encoded by the PSMA1 gene |
| Immunogen | Amino acids 159-204 (MSIGARSQSARTYLERHMSEFMECNLNELVKHGLRALRETLPAEQD) from the human protein were used as the immunogen for the PSMA1 antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the PSMA1 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization | nuclear, Cytoplasmic |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | PSMA1 / Proteasome 20S alpha 1 |
| Short name | PSMA1 Antibody / Proteasome 20S alpha 1 |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | proteasome subunit a classification-1 isoform 3 (Antibody to) / protein degradation aggregate 20S a 1 |
| Alternative technique | antibodies |
| Alternative to gene target | HC2 and HEL-S-275 and NU and PROS30, PSMA1 and IDBG-545891 and ENSG00000256206 and 5682, alpha-subunit complex and cellular component this GO :0051603 and proteolysis involved in cellular protein catabolic process and biological process, nuclei, this GO :0004175 and endopeptidase activity and molecular function this GO :0004298 and threonine-type endopeptidase activity and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005839 and proteasome core complex and cellular component this GO :0006511 and ubiquitin-dependent protein catabolic process and biological process this GO :0019773 and proteasome core complex, this GO :0004175: endopeptidase activity, this GO :0004175: endopeptidase activity and also this GO :0004298: threonine-type endopeptidase activity, this GO :0004298: threonine-type endopeptidase activity, threonine-type endopeptidase activity, proteasome subunit alpha type-1 isoform 3 |
| Identity | 9530 |
| Gene | PSMA1 |
| Long gene name | proteasome subunit alpha 1 |
| Synonyms gene name | 1 , alpha type, macropain) subunit, proteasome (prosome |
| Synonyms | HC2 NU PROS30 MGC14542 MGC14575 MGC14751 MGC1667 MGC21459 MGC22853 MGC23915 |
| Locus | 11p15, 2 |
| Discovery year | 1995-05-03 |
| GenBank acession | X61969 |
| Entrez gene record | 5682 |
| Pubmed identfication | 1398136 2025653 |
| RefSeq identity | NM_002786 |
| Classification | Proteasome |
| Havana BLAST/BLAT | OTTHUMG00000165825 |