| Long name | PSMC1 Primary Polyclonal Antibody |
| Also known as | PSMC1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | PSMC1 |
| Specificity | This is a highly specific antibody against PSMC1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PSMC1/Proteasome 19S S4 |
| Gene ID number | 5700 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits, An essential function of a modified proteasome, Finally, Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway, The 19S regulator is composed of a base, The 20S core is composed of 4 rings of 28 non-identical subunits, This gene encodes one of the ATPase subunits, This subunit also interacts with the adenovirus E1A protein and this interaction alters the activity of the proteasome, This subunit and a 20S core alpha subunit interact specifically with the hepatitis B virus X protein, a 20S core and a 19S regulator, a member of the triple-A family of ATPases which have a chaperone-like activity, a progressive neurodegenerative disorder, a protein critical to viral replication, and a lid, is the processing of class I MHC peptides, suggesting a role for the proteasome in the development of spinocerebellar ataxia type 7, the immunoproteasome, this subunit interacts with ataxin-7, which contains 6 ATPase subunits and 2 non-ATPase subunits, which contains up to 10 non-ATPase subunits, The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | P26S4, PRS4_HUMAN, PSMC 1, PSMC1, Proteasome 26S ATPase subunit 1, Proteasome 26S subunit ATPase 1, Proteasome prosome macropain 26S subunit ATPase 1, S4, p56, 26S protease regulatory subunit 4 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | PSMC1 |
| Short name | PSMC1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 1 (Antibody to), ATPase, macropain) 26S subunit, proteasome (prosome |
| Alternative technique | antibodies |
| Alternative to gene target | 1, ATPase, P26S4 and p56 and S4, PSMC1 and IDBG-15761 and ENSG00000100764 and 5700, PSMC1 and IDBG-646926 and ENSBTAG00000005426 and 506238, Psmc1 and IDBG-163709 and ENSMUSG00000021178 and 19179, TAP-dependent and biological process this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005838 and proteasome regulatory particle and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006281 and DNA repair and biological process this GO :0006310 and DNA recombination and biological process this GO :0006508 and proteolysis and biological process this GO :0006521 and regulation of cellular amino acid metabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0006977 and DNA damage response, macropain) 26S subunit, nuclei, poly(A) RNA binding, signal transduction by p53 class mediator resulting in cell cycle arrest and biological process this GO :0008233 and peptidase activity and molecular function this GO :0009378 and four-way junction helicase activity and molecular function this GO :0010467 and gene expression and biological process this GO :0016020 and membrane and cellular component this GO :0016032 and viral process and biological process this GO :0016070 and RNA metabolic process and biological process this GO :0016071 and mRNA metabolic process and biological process this GO :0016787 and hydrolase activity and molecular function this GO :0016887 and ATPase activity and molecular function this GO :0017025 and TBP-class protein binding and molecular function this GO :0017111 and nucleoside-triphosphatase activity and molecular function this GO :0022624 and proteasome accessory complex and cellular component this GO :0030163 and protein catabolic process and biological process this GO :0031145 and anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0034641 and cellular nitrogen compound metabolic process and biological process this GO :0042590 and antigen processing and presentation of exogenous peptide antigen via MHC class I and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0051436 and negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051437 and positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051439 and regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process, this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0000209 and protein polyubiquitination and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0000502 and proteasome complex and cellular component this GO :0002474 and antigen processing and presentation of peptide antigen via MHC class I and biological process this GO :0002479 and antigen processing and presentation of exogenous peptide antigen via MHC class I, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0008233: peptidase activity and also this GO :0009378: four-way junction helicase activity and also this GO :0016787: hydrolase activity and also this GO :0016887: ATPase activity and also this GO :0017025: TBP-class protein binding and also this GO :0017111: nucleoside-triphosphatase activity and also this GO :0044822: poly(A) RNA binding, this GO :0005524: ATP binding, this GO :0008233: peptidase activity, this GO :0009378: four-way junction helicase activity, this GO :0016787: hydrolase activity, this GO :0016887: ATPase activity, this GO :0017025: TBP-class protein binding, this GO :0017111: nucleoside-triphosphatase activity, this GO :0044822: poly(A) RNA binding, proteasome (prosome |
| Identity | 9547 |
| Gene | PSMC1 |
| Long gene name | ATPase 1 , proteasome 26S subunit |
| Synonyms gene name | 1 , ATPase, macropain) 26S subunit, proteasome (prosome |
| Synonyms | S4 p56 |
| Locus | 14q32, 11 |
| Discovery year | 1995-11-27 |
| GenBank acession | L02426 |
| Entrez gene record | 5700 |
| Pubmed identfication | 9473509 |
| RefSeq identity | NM_002802 |
| Classification | AAA ATPases Proteasome |
| Havana BLAST/BLAT | OTTHUMG00000171019 |
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