| Long name | PSMD6 Primary Polyclonal Antibody |
| Also known as | PSMD6 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | PSMD6 |
| Specificity | This is a highly specific antibody against PSMD6 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PSMD6 |
| Gene ID number | 5716 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits, An essential function of a modified proteasome, It acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins, Proteasome 26S S10 is a non-ATPase subunit of the 19S regulator, Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway, Pseudogenes have been identified on chromosomes 3 and 20, The 19S regulator is composed of a base, The 20S core is composed of 4 rings of 28 non-identical subunits, Two transcripts encoding different isoforms have been described, a 20S core and a 19S regulator, and a lid, is the processing of class I MHC peptides, the immunoproteasome, which contains 6 ATPase subunits and 2 non-ATPase subunits, which contains up to 10 non-ATPase subunits, The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 26S proteasome regulatory subunit RPN7, 26S proteasome regulatory subunit S10, 6, Breast cancer-associated protein SGA-113M, KIAA0107, P44S10, PFAAP4, PSMD6_HUMAN, Phosphonoformate immuno-associated protein 4, Proteasome 26S S10, Proteasome prosome, Proteasome regulatory particle subunit p44S10, Rpn7, S10 antibody SGA-113M, macropain 26S subunit, non-ATPase, p42A, 26S proteasome non-ATPase regulatory subunit 6 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | PSMD6 |
| Short name | PSMD6 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 6 (Antibody to), macropain) 26S subunit, non-ATPase, proteasome (prosome |
| Alternative technique | antibodies |
| Alternative to gene target | 6, ATPase activity, BT, PSMD6 and IDBG-43018 and ENSG00000163636 and 9861, Psmd6 and IDBG-132715 and ENSMUSG00000021737 and 66413, TAP-dependent and biological process this GO :0005515 and protein binding and molecular function this GO :0005654 and nucleoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006508 and proteolysis and biological process this GO :0006521 and regulation of cellular amino acid metabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0006977 and DNA damage response, macropain) 26S subunit, non-ATPase, nuclei, p42A and p44S10 and Rpn7 and S10 and SGA-113M, signal transduction by p53 class mediator resulting in cell cycle arrest and biological process this GO :0010467 and gene expression and biological process this GO :0016032 and viral process and biological process this GO :0016070 and RNA metabolic process and biological process this GO :0016071 and mRNA metabolic process and biological process this GO :0016887 and ATPase activity and molecular function this GO :0022624 and proteasome accessory complex and cellular component this GO :0031145 and anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0034641 and cellular nitrogen compound metabolic process and biological process this GO :0042590 and antigen processing and presentation of exogenous peptide antigen via MHC class I and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0051436 and negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051437 and positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051439 and regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0000209 and protein polyubiquitination and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0000502 and proteasome complex and cellular component this GO :0002474 and antigen processing and presentation of peptide antigen via MHC class I and biological process this GO :0002479 and antigen processing and presentation of exogenous peptide antigen via MHC class I, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0016887: ATPase activity, this GO :0016887: ATPase activity, 88479 and IDBG-645134 and ENSBTAG00000015112 and 538625, proteasome (prosome |
| Identity | 9564 |
| Gene | PSMD6 |
| Long gene name | non-ATPase 6 , proteasome 26S subunit |
| Synonyms gene name | 6 , macropain) 26S subunit, non-ATPase, proteasome (prosome |
| Synonyms | S10 p44S10 KIAA0107 Rpn7 |
| Locus | 3p14, 1 |
| Discovery year | 1995-12-06 |
| GenBank acession | AF215935 |
| Entrez gene record | 9861 |
| Pubmed identfication | 10723133 |
| RefSeq identity | NM_014814 |
| Classification | Proteasome |
| Havana BLAST/BLAT | OTTHUMG00000158765 |
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