| Long name | ALEXA FLUOR 350 Conjugated, PTK2(Tyr576+Tyr577) Polyclonal Antibody |
| Also known as | Anti-PTK2 Tyr576+Tyr577 PAb ALEXA FLUOR 350 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 350, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | PTK2 Tyr576+Tyr577 |
| Specificity | This is a highly specific antibody against PTK2 Tyr576+Tyr577 |
| Modification | Phosphorylation |
| Modification Site | Tyr576+Tyr577 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human PTK2 around the phosphorylation site of Tyr576+Tyr577 |
| Gene ID Number | 5747 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, Cell membrane, Cytoplasmic side, Note=Constituent of focal adhesions, Peripheral membrane protein, Plays a potential role in oncogenic transformations resulting in increased kinase activity, [SUBCELLULAR LOCATION] Cell junction, focal adhesion, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy, proliferation and apoptosis, Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 343nm/442nm |
| Synonyms | FAK FADK FAK1 PPP1R71 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 350, Alexa Fluor |
| Gene target | PTK2(Tyr576+Tyr577) |
| Short name | PTK2(Tyr576+Tyr577) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 350 |
| Alternative name | ALEXA FLUOR 350, PTK2 protein tyrosine kinase 2(Tyr576+Tyr577) (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | FADK and FAK and FAK1 and FRNK and p125FAK and pp125FAK and PPP1R71, PTK2 and IDBG-37147 and ENSG00000169398 and 5747, PTK2 and IDBG-643924 and ENSBTAG00000009578 and 506270, Ptk2 and IDBG-148322 and ENSMUSG00000022607 and 14083, nuclei, this GO :0000226 and microtubule cytoskeleton organization and biological process this GO :0001525 and angiogenesis and biological process this GO :0001568 and blood vessel development and biological process this GO :0001570 and vasculogenesis and biological process this GO :0001764 and neuron migration and biological process this GO :0001890 and placenta development and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0003007 and heart morphogenesis and biological process this GO :0003779 and actin binding and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004715 and non-membrane spanning protein tyrosine kinase activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005815 and microtubule organizing center and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0005938 and cell cortex and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0006921 and cellular component disassembly involved in execution phase of apoptosis and biological process this GO :0007165 and signal transduction and biological process this GO :0007172 and signal complex assembly and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007411 and axon guidance and biological process this GO :0007596 and blood coagulation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008360 and regulation of cell shape and biological process this GO :0008432 and JUN kinase binding and molecular function this GO :0009790 and embryo development and biological process this GO :0010594 and regulation of endothelial cell migration and biological process this GO :0014068 and positive regulation of phosphatidylinositol 3-kinase signaling and biological process this GO :0016324 and apical plasma membrane and cellular component this GO :0016772 and transferase activity, this GO :0003779: actin binding, this GO :0003779: actin binding and also this GO :0004672: protein kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0004715: non-membrane spanning protein tyrosine kinase activity and also this GO :0004871: signal transducer activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0008432: JUN kinase binding and also this GO :0016772: transferase activity, this GO :0004672: protein kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004715: non-membrane spanning protein tyrosine kinase activity, this GO :0004871: signal transducer activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0008432: JUN kinase binding, this GO :0016772: transferase activity, this GO :0019901: protein kinase binding, this GO :0042169: SH2 domain binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019901: protein kinase binding and also this GO :0042169: SH2 domain binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0021955 and central nervous system neuron axonogenesis and biological process this GO :0022408 and negative regulation of cell-cell adhesion and biological process this GO :0030010 and establishment of cell polarity and biological process this GO :0030027 and lamellipodium and cellular component this GO :0030168 and platelet activation and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0032319 and regulation of Rho GTPase activity and biological process this GO :0033628 and regulation of cell adhesion mediated by integrin and biological process this GO :0038007 and netrin-activated signaling pathway and biological process this GO :0038096 and Fc-gamma receptor signaling pathway involved in pha this GO cytosis and biological process this GO :0040023 and establishment of nucleus localization and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042169 and SH2 domain binding and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043542 and endothelial cell migration and biological process this GO :0043552 and positive regulation of phosphatidylinositol 3-kinase activity and biological process this GO :0045087 and innate immune response and biological process this GO :0045667 and regulation of osteoblast differentiation and biological process this GO :0045860 and positive regulation of protein kinase activity and biological process this GO :0046621 and negative regulation of organ growth and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048013 and ephrin receptor signaling pathway and biological process this GO :0048870 and cell motility and biological process this GO :0050771 and negative regulation of axonogenesis and biological process this GO :0051493 and regulation of cytoskeleton organization and biological process this GO :0051893 and regulation of focal adhesion assembly and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0051964 and negative regulation of synapse assembly and biological process this GO :0060396 and growth hormone receptor signaling pathway and biological process this GO :2000060 and positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process and biological process this GO :2000811 and negative regulation of anoikis and biological process, PTK2 protein tyrosine kinase 2 |
| Identity | 9611 |
| Gene | PTK2 |
| Long gene name | protein tyrosine kinase 2 |
| Synonyms gene name | PTK2 protein tyrosine kinase 2 |
| Synonyms name | protein phosphatase 1, regulatory subunit 71 |
| Locus | 8q24, 3 |
| Discovery year | 1992-10-02 |
| GenBank acession | L13616 |
| Entrez gene record | 5747 |
| Pubmed identfication | 8422239 |
| RefSeq identity | NM_005607 |
| Classification | Protein phosphatase 1 regulatory subunits FERM domain containing |
| Havana BLAST/BLAT | OTTHUMG00000067438 |
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