Name : PTPN11 (246CT9.8.2) Monoclonal Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :328
SKU : GEN7303106513
| Long name | 2) Monoclonal Antibody, 8, PTPN11 (246CT9 |
| Also known as | 2) Monoclonal Antibody, 8, PTPN11 (246CT9 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | PTPN11 |
| Specificity | This is a highly specific antibody against PTPN11 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 2, 246CT9, 8 |
| Source | This PTPN11 monoclonal antibody is generated from mouse immunized with PTPN11 recombinant protein |
| Gene ID number | 5781 |
| Swiss Prot | Q06124 |
| Tested Applications | WB |
| Recommended dilutions | WB(1:100~500) |
| Cross reactivity | Mouse |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity, Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus |
| Purification method | 09% (W/V) sodium azide, Mouse monoclonal antibody supplied in crude ascites with 0 |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | BPTP3, JMML, METCDS, NS1, PTP-1D, PTP-2C, PTP2C, PTPN11, Protein-tyrosine phosphatase 1D, Protein-tyrosine phosphatase 2C, SH-PTP2, SH-PTP3, SHP-2, SHP2, SHPTP2, Tyrosine-protein phosphatase non-receptor type 11, CFC |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | 2) Monoclonal, 8, PTPN11 (246CT9 |
| Short name | 2) Monoclonal Antibody, 8, PTPN11 (246CT9 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 2) monoclonal (Antibody to), 8, PTPN11 (246CT9 |
| Alternative technique | antibodies |
| Identity | 9644 |
| Gene | PTPN11 |
| Long gene name | non-receptor type 11 , protein tyrosine phosphatase |
| Synonyms gene | NS1 |
| Synonyms gene name | Noonan syndrome 1 |
| Synonyms | BPTP3 SH-PTP2 SHP-2 PTP2C SHP2 |
| Locus | 12q24, 13 |
| Discovery year | 1993-03-03 |
| GenBank acession | D13540 |
| Entrez gene record | 5781 |
| Pubmed identfication | 7894486 1280823 |
| Classification | Protein tyrosine phosphatases, non-receptor type SH2 domain containing |
| Havana BLAST/BLAT | OTTHUMG00000134334 |
| Locus Specific Databases | LRG_614 |