Name : PTPN11 (Tyr584) Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :350
SKU : GEN7992922732
| Long name | ALEXA FLUOR 488 Conjugated, PTPN11 (Tyr584) Polyclonal Antibody |
| Also known as | Anti-PTPN11 Tyr584 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | PTPN11 Tyr584 |
| Specificity | This is a highly specific antibody against PTPN11 Tyr584 |
| Modification | Phosphorylation |
| Modification Site | Tyr584 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 550-597/597 |
| Subcellular location | Cytoplasm |
| Source | KLH conjugated synthetic phosphopeptide derived from human PTPN11 around the phosphorylation site of Tyr584 |
| Gene ID Number | 5781 |
| Swiss Prot | Q06124 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity, Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | BPTP3 SH-PTP2 SHP-2 PTP2C SHP2 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the PTPN11 (Tyr584) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | PTPN11 (Tyr584) |
| Short name | PTPN11 (Tyr584) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, PTPN11 (Tyr584) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 9644 |
| Gene | PTPN11 |
| Long gene name | non-receptor type 11 , protein tyrosine phosphatase |
| Synonyms gene | NS1 |
| Synonyms gene name | Noonan syndrome 1 |
| Locus | 12q24, 13 |
| Discovery year | 1993-03-03 |
| GenBank acession | D13540 |
| Entrez gene record | 5781 |
| Pubmed identfication | 7894486 1280823 |
| Classification | Protein tyrosine phosphatases, non-receptor type SH2 domain containing |
| Havana BLAST/BLAT | OTTHUMG00000134334 |
| Locus Specific Databases | LRG_614 |