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PTPN11 (Tyr584) Antibody, FITC Conjugated

PTPN11 (Tyr584) Antibody, FITC Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, PTPN11 (Tyr584) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPTPN11 Tyr584
Specificity This phosphorylation site is homologous across the listed cross reactive species, This is a highly specific antibody against PTPN11 Tyr584
ModificationPhosphorylation
Modification siteTyr584
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range550-597/597
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human PTPN11 around the phosphorylation site of Tyr584
Gene ID number5781
Swiss ProtQ06124
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity, Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms BPTP3 SH-PTP2 SHP-2 PTP2C SHP2
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPTPN11 (Tyr584) Conjugated
Short name FITC Conjugated, PTPN11 (Tyr584) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, PTPN11 (Tyr584) (Antibody to)
Alternative techniqueantibodies
Identity 9644
Gene PTPN11
Long gene name non-receptor type 11 , protein tyrosine phosphatase
Synonyms gene NS1
Synonyms gene name Noonan syndrome 1
Locus 12q24, 13
Discovery year 1993-03-03
GenBank acession D13540
Entrez gene record 5781
Pubmed identfication 7894486 1280823
Classification Protein tyrosine phosphatases, non-receptor type SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000134334
Locus Specific Databases LRG_614

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