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PTPN5/STEP Antibody, FITC Conjugated

PTPN5/STEP Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, PTPN5/STEP Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPTPN5/STEP
SpecificityThis is a highly specific antibody against PTPN5/STEP
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human PTPN5
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Isolated from mouse brain, STEP depresses both NMDAR single-channel activity and synaptic currents, STEP family members are expressed in the dopaminoceptive neurons of the CNS, STEP61 contains a single tyrosine phosphatase domain, STEP61 dephosphorylates Tyr-420 residue and may thus regulate Fyn activity in PSDs, The STEP protein regulates the N-methyl-d-aspartate receptor (NMDAR) complex, The STEP61 protein associates with the Src family kinase member Fyn when Fyn is phosphorylated at Tyr-420 and not Tyr-431, The human STEP gene maps to chromosome 11p15, The membrane-associated STEP61 isoform localizes in the postsynaptic densities (PSDs) of striatal neurons, Upon association, the STEP20 isoform lacks the conserved tyrosine phosphatase domain, two proline-rich domains and two transmembrane domains, with highest expression in the basal ganglia and related structures, 1, 2-p15, The brain-specific STEP (striatal enriched phosphatase) family of protein tyrosine phosphatases (PTPs) comprises both transmembrane and cytosolic protein members which are the products of alternative splicing
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms STEP PTPSTEP STEP61
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPTPN5/ Conjugated
Short name FITC Conjugated, PTPN5/STEP Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, PTPN5/STEP (Antibody to)
Alternative techniqueantibodies
Identity 9657
Gene PTPN5
Long gene name non-receptor type 5 , protein tyrosine phosphatase
Synonyms gene name non-receptor type 5 (striatum-enriched) , protein tyrosine phosphatase
Synonyms name striatal-enriched protein tyrosine phosphatase
Locus 11p15, 1
Discovery year 1992-02-12
GenBank acession BC064807
Entrez gene record 84867
Pubmed identfication 1714595
RefSeq identity NM_001039970
Classification Protein tyrosine phosphatases, non-receptor type
Havana BLAST/BLAT OTTHUMG00000134304

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