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PXR Antibody

PXR Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePXR Primary Polyclonal Antibody
Also known asPXR PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPXR
SpecificityThis is a highly specific antibody against PXR
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range80-130/434
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PXR
Gene ID number8856
Swiss ProtO75469
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Activated by naturally occurring steroids, Activated by the antibiotic rifampicin and various plant metabolites, Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes, Response to specific ligands is species-specific, Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, and isoflavones, colupulone, drugs and endogenous compounds, guggulipid, such as hyperforin, such as pregnenolone and progesterone, Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names NR1I2, Nuclear receptor subfamily 1 group I member 2, ONR1, Orphan nuclear receptor PAR1, Orphan nuclear receptor PXR, PAR, PAR1, PAR2, PARq, PRR, PXR, Pregnane X receptor, SAR, SXR, Steroid and xenobiotic receptor, BXR
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPXR
Short namePXR Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePXR (Antibody to)
Alternative techniqueantibodies
Identity 7968
Gene NR1I2
Long gene name nuclear receptor subfamily 1 group I member 2
Synonyms gene name group I, member 2 , nuclear receptor subfamily 1
Synonyms ONR1 PXR BXR SXR PAR2
Synonyms name pregnane X receptor orphan nuclear receptor PXR
Locus 3q13, 33
Discovery year 1999-04-23
GenBank acession AF061056
Entrez gene record 8856
Pubmed identfication 9727070 9770465
Classification Nuclear hormone receptors
Havana BLAST/BLAT OTTHUMG00000159400

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