Name : PXR Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN7888212438
| Long name | ALEXA FLUOR 647 Conjugated, PXR Polyclonal Antibody |
| Also known as | Anti-PXR PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | PXR |
| Specificity | This is a highly specific antibody against PXR |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 80-130/434 |
| Subcellular location | Nucleus |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PXR |
| Gene ID Number | 8856 |
| Swiss Prot | O75469 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Activated by naturally occurring steroids, Activated by the antibiotic rifampicin and various plant metabolites, Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes, Response to specific ligands is species-specific, Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, and isoflavones, colupulone, drugs and endogenous compounds, guggulipid, such as hyperforin, such as pregnenolone and progesterone, Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | ONR1 PXR BXR SXR PAR2 |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the PXR Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | PXR |
| Short name | PXR Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, PXR (Antibody to) |
| Alternative technique | antibodies |
| Identity | 7968 |
| Gene | NR1I2 |
| Long gene name | nuclear receptor subfamily 1 group I member 2 |
| Synonyms gene name | group I, member 2 , nuclear receptor subfamily 1 |
| Synonyms name | pregnane X receptor orphan nuclear receptor PXR |
| Locus | 3q13, 33 |
| Discovery year | 1999-04-23 |
| GenBank acession | AF061056 |
| Entrez gene record | 8856 |
| Pubmed identfication | 9727070 9770465 |
| Classification | Nuclear hormone receptors |
| Havana BLAST/BLAT | OTTHUMG00000159400 |