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PXR Antibody, Cy5.5 Conjugated

PXR Antibody, Cy5.5 Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Cy5, 5 Conjugated, PXR Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation Cy5, 5, 5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPXR
SpecificityThis is a highly specific antibody against PXR
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range80-130/434
Subcellular locationNucleus
SourceKLH conjugated synthetic peptide derived from human PXR
Gene ID number8856
Swiss ProtO75469
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Activated by naturally occurring steroids, Activated by the antibiotic rifampicin and various plant metabolites, Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes, Response to specific ligands is species-specific, Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, and isoflavones, colupulone, drugs and endogenous compounds, guggulipid, such as hyperforin, such as pregnenolone and progesterone, Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission675nm/694nm
Synonyms ONR1 PXR BXR SXR PAR2
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene targetPXR Conjugated
Short name Conjugated, PXR Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label5, Cy5
Alternative name cyanine 5, 5 coupled, PXR (Antibody to)
Alternative techniqueantibodies
Identity 7968
Gene NR1I2
Long gene name nuclear receptor subfamily 1 group I member 2
Synonyms gene name group I, member 2 , nuclear receptor subfamily 1
Synonyms name pregnane X receptor orphan nuclear receptor PXR
Locus 3q13, 33
Discovery year 1999-04-23
GenBank acession AF061056
Entrez gene record 8856
Pubmed identfication 9727070 9770465
Classification Nuclear hormone receptors
Havana BLAST/BLAT OTTHUMG00000159400

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