Name : R-PTP eta (T23-5E6) Monoclonal Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :362
SKU : GEN2994313451
| Long name | R-PTP eta (T23-5E6) Monoclonal Antibody |
| Also known as | R-PTP eta (T23-5E6) Monoclonal Antibody |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | R-PTP eta |
| Specificity | This is a highly specific antibody against R-PTP eta |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | T23-5E6 |
| Source | Recombinant human protein purified from E, coli |
| Swiss Prot | Q12913 |
| Tested Applications | WB |
| Recommended dilutions | WB (1:2000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | CD148, HPTPeta, PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, R-PTP-ETA) is an enzyme that in humans is encoded by the PTPRJ gene, SCC1, This PTP is present in all hematopoietic lineages, This PTP possesses an extracellular region containing five fibronectin type III repeats, This PTP was also found to dephosphorylate PDGF beta receptor, a single transmembrane region, and a single intracytoplasmic catalytic domain, and may be involved in UV-induced signal transduction, and oncogenic transformation, and thus represents a receptor-type PTP, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 (PLCG1) and Linker for Activation of T Cells (LAT), differentiation, mitotic cycle, Receptor-type tyrosine-protein phosphatase eta(Also known as DEP1, [1][2][3] The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family, [3] PTPRJ has been shown to interact with CTNND1, [4] |
| Purification method | Ammonium sulfate precipitation |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | R-PTP eta (T23-5E6) Monoclonal |
| Short name | R-PTP eta (T23-5E6) Monoclonal Antibody |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | R-PTP eta (T23-5E6) monoclonal (Antibody to) |
| Alternative technique | antibodies |