RAB13 (3250CT845.37.29) Monoclonal Antibody

RAB13 (3250CT845.37.29) Monoclonal Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 281

Size 0.1ml

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Long name	29) Monoclonal Antibody, 37, RAB13 (3250CT845
Also known as	29) Monoclonal Antibody, 37, RAB13 (3250CT845
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	RAB13
Specificity	This is a highly specific antibody against RAB13
Modification(s)	None
Modification site(s)	Unmodified antibody
Clonality	Monoclonal
Clone number	29, 3250CT845, 37
Source	This RAB13 antibody is generated from a mouse immunized with a recombinant protein between 1-203 amino acids from human RAB13
Gene ID number	5872
Swiss Prot	P51153
Tested Applications	WB
Recommended dilutions	WB(1:1000)
Cross reactivity	Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	Also involved in neurite outgrowth, Finally, Has also been proposed to play a role in post-Golgi membrane trafficking from the TGN to the recycling endosome, Moreover, Plays also a role in angiogenesis through regulation of endothelial cells chemotaxis, Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, That Rab is involved in endocytic recycling and regulates the transport to the plasma membrane of transmembrane proteins like the tight junction protein OCLN/occludin, Thereby, Through its role in tight junction assembly, from the formation of transport vesicles to their fusion with membranes, it has been involved in insulin-induced transport to the plasma membrane of the glucose transporter GLUT4 and therefore may play a role in glucose homeostasis, it may also regulate tight junction assembly by activating the PKA signaling pathway and by reorganizing the actin cytoskeleton through the activation of the downstream effectors PRKACA and MICALL2 respectively, it regulates the assembly and the activity of tight junctions, may play a role in the establishment of Sertoli cell barrier, movement, tethering and fusion, The small GTPases Rab are key regulators of intracellular membrane trafficking
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	Cell growth-inhibiting gene 4 protein, RAB13, Ras-related protein Rab-13, GIG4
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About	Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target	29) Monoclonal, 37, RAB13 (3250CT845
Short name	29) Monoclonal Antibody, 37, RAB13 (3250CT845
Technique	Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name	member RAS oncogene family (3250CT845, 29) monoclonal (Antibody to), 37, RAB13
Alternative technique	antibodies
Alternative to gene target	RAB13 and IDBG-102843 and ENSG00000143545 and 5872, RAB13 and IDBG-632584 and ENSBTAG00000017604 and 514541, Rab13 and IDBG-166105 and ENSMUSG00000027935 and 68328, member RAS oncogene family, nuclei, protein kinase A catalytic subunit binding, this GO :0003924 and GTPase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005525 and GTP binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005802 and trans- this GO lgi network and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0005923 and tight junction and cellular component this GO :0006184 and GTP catabolic process and biological process this GO :0006886 and intracellular protein transport and biological process this GO :0006913 and nucleocytoplasmic transport and biological process this GO :0007165 and signal transduction and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0010737 and protein kinase A signaling and biological process this GO :0015031 and protein transport and biological process this GO :0016020 and membrane and cellular component this GO :0016197 and endosomal transport and biological process this GO :0016328 and lateral plasma membrane and cellular component this GO :0030027 and lamellipodium and cellular component this GO :0030139 and endocytic vesicle and cellular component this GO :0030658 and transport vesicle membrane and cellular component this GO :0030659 and cytoplasmic vesicle membrane and cellular component this GO :0030866 and cortical actin cytoskeleton organization and biological process this GO :0031175 and neuron projection development and biological process this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0032456 and endocytic recycling and biological process this GO :0032593 and insulin-responsive compartment and cellular component this GO :0032869 and cellular response to insulin stimulus and biological process this GO :0034236 and protein kinase A catalytic subunit binding and molecular function this GO :0035767 and endothelial cell chemotaxis and biological process this GO :0043005 and neuron projection and cellular component this GO :0044795 and trans- this GO lgi network to recycling endosome transport and biological process this GO :0055037 and recycling endosome and cellular component this GO :0055038 and recycling endosome membrane and cellular component this GO :0061024 and membrane organization and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070830 and tight junction assembly and biological process this GO :0072659 and protein localization to plasma membrane and biological process this GO :0090002 and establishment of protein localization to plasma membrane and biological process this GO :0097368 and establishment of Sertoli cell barrier and biological process this GO :1902463 and protein localization to cell leading edge and biological process, this GO :0003924: GTPase activity, this GO :0003924: GTPase activity and also this GO :0005515: protein binding and also this GO :0005525: GTP binding and also this GO :0034236: protein kinase A catalytic subunit binding, this GO :0005515: protein binding, this GO :0005525: GTP binding, this GO :0034236: protein kinase A catalytic subunit binding, RAB13
Identity	9762
Gene	RAB13
Long gene name	RAB13, member RAS oncogene family
Locus	1q21, 3
Discovery year	1998-01-21
GenBank acession	X75593
Entrez gene record	5872
Pubmed identfication	8294494
RefSeq identity	NM_002870
Classification	RAB, member RAS oncogene GTPases
Havana BLAST/BLAT	OTTHUMG00000036589

RAB13 (3250CT845.37.29) Monoclonal Antibody

RAB13 (3250CT845.37.29) Monoclonal Antibody size: 0.1ml 281

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