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RAB5 Antibody, ALEXA FLUOR 594

RAB5 Antibody, ALEXA FLUOR 594 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 594 Conjugated, RAB5 Polyclonal Antibody
Also known asAnti-RAB5 PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRAB5
SpecificityThis is a highly specific antibody against RAB5
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RAB5
Gene ID Number5868
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen CXC, Due to the presence of truncated sequences in this CD, GTPase activating proteins (GAPs) interact with GTP-bound Rab and accelerate the hydrolysis of GTP to GDP, Guanine nucleotide exchange factors (GEFs) interact with GDP-bound Rabs to promote the formation of the GTP-bound state, In mammals, In yeast, Lipid binding is essential for membrane attachment, Most Rab GTPases contain a lipid modification site at the C-terminus, Rab5 GTPases localize to early endosomes and regulate fusion of clathrin-coated vesicles to early endosomes and fusion between early endosomes, Rabs are further regulated by guanine nucleotide dissociation inhibitors (GDIs), The members of this subfamily are involved in endocytosis and endocytic-sorting pathways, This subfamily includes Rab5 and Rab22 of mammals, Ypt51/Ypt52/Ypt53 of yeast, Ypt51p family members similarly regulate membrane trafficking through prevacuolar compartments, a key feature of most Rab proteins, and RabF of plants, or CCX, the lipid modification site is not available for annotation, which facilitate Rab recycling by masking C-terminal lipid binding and promoting cytosolic localization, with sequence motifs CC, Rab5-related subfamily
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetRAB5
Short nameRAB5 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, RAB5 (Antibody to)
Alternative techniqueantibodies
Identity 9783
Gene RAB5A
Long gene name RAB5A, member RAS oncogene family
Synonyms gene RAB5
Synonyms name RAS-associated protein RAB5A
Locus 3p24, 3
Discovery year 1990-01-22
Entrez gene record 5868
Pubmed identfication 1999336
RefSeq identity NM_004162
Classification RAB, member RAS oncogene GTPases
Havana BLAST/BLAT OTTHUMG00000129889

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