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RAB7 Antibody, Biotin Conjugated

RAB7 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, RAB7 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRAB7
SpecificityThis is a highly specific antibody against RAB7
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range110-160/207
SourceKLH conjugated synthetic peptide derived from human RAB7
Gene ID number7879
Swiss ProtP51149
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Also involved in regulation of some specialized endosomal membrane trafficking, Controls the endosomal trafficking and neurite outgrowth signaling of NTRK1/TRKA, Governs early-to-late endosomal maturation, In concert with RAC1, Microbial pathogens possess survival strategies governed by RAB7A, Mycobacterium), Plays a central role, Plays a role in the fusion of phagosomes with lysosomes, Plays a role in the maturation and acidification of phagosomes that engulf pathogens, Plays important roles in microbial pathogen infection and survival, Regulates the endocytic trafficking of the EGF-EGFR complex by regulating its lysosomal degradation, Salmonella) and sometimes by excluding RAB7A function (e, and endosome-lysosome transport through different protein-protein interaction cascades, as well as in participating in the life cycle of viruses, but also in many other cellular and physiological events, microtubule minus-end as well as plus-end directed endosomal migration and positioning, neurotrophin transport in the axons of neurons and lipid metabolism, not only in endosomal traffic, nutrient-transportor mediated nutrient uptake, pathogen-induced phagosomes (or vacuoles) and autophagosomes, plays a role in regulating the formation of RBs (ruffled borders) in osteoclasts, sometimes by employing RAB7A function (e, such as S, such as growth-factor-mediated cell signaling, such as maturation of melanosomes, Key regulator in endo-lysosomal trafficking, aureus and M, g, g, tuberculosis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetRAB7 Conjugated
Short name Conjugated, RAB7 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, RAB7 (Antibody to)
Alternative techniqueantibodies
Identity 9788
Gene RAB7A
Long gene name RAB7A, member RAS oncogene family
Synonyms gene RAB7
Synonyms gene name RAB7, member RAS oncogene family
Locus 3q21, 3
Discovery year 1999-03-24
GenBank acession X93499
Entrez gene record 7879
Pubmed identfication 9126495 9428630
Classification RAB, member RAS oncogene GTPases
Havana BLAST/BLAT OTTHUMG00000159812
Locus Specific Databases LRG_266

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