| Long name | RAB8A Primary Polyclonal Antibody |
| Also known as | RAB8A PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | RAB8A |
| Specificity | This is a highly specific antibody against RAB8A |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 143-155/207 |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RAB8A |
| Gene ID number | 4218 |
| Swiss Prot | P61006 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), May play a role in insulin-induced transport to the plasma membrane of the glucose transporter GLUT4 and therefore play a role in glucose homeostasis, PARD3, PRKCI, Plays an important role in ciliogenesis, RAB3IP, Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, That Rab is involved in polarized vesicular trafficking and neurotransmitter release, Together with MICALL2, Together with MYO5B and RAB11A participates in epithelial cell polarization, Together with RAB11A, apical surface formation and lumenogenesis, from the formation of transport vesicles to their fusion with membranes, may also regulate adherens junction assembly, movement, tethering and fusion, the exocyst complex, The small GTPases Rab are key regulators of intracellular membrane trafficking |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Oncogene c-mel, RAB8, RAB8A, Ras-related protein Rab-8A, MEL |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | RAB8A |
| Short name | RAB8A Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | member RAS oncogene family (Antibody to), RAB8A |
| Alternative technique | antibodies |
| Alternative to gene target | MEL and RAB8, RAB8A and IDBG-35329 and ENSG00000167461 and 4218, RAB8A and IDBG-642338 and ENSBTAG00000038696 and 100125881, Rab8a and IDBG-167493 and ENSMUSG00000003037 and 17274, member RAS oncogene family, nuclei, protein kinase binding, this GO :0000086 and G2/M transition of mitotic cell cycle and biological process this GO :0000139 and this GO lgi membrane and cellular component this GO :0000278 and mitotic cell cycle and biological process this GO :0003924 and GTPase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005525 and GTP binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005813 and centrosome and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005929 and cilium and cellular component this GO :0006184 and GTP catabolic process and biological process this GO :0006886 and intracellular protein transport and biological process this GO :0006904 and vesicle docking involved in exocytosis and biological process this GO :0006913 and nucleocytoplasmic transport and biological process this GO :0007165 and signal transduction and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0007409 and axonogenesis and biological process this GO :0014069 and postsynaptic density and cellular component this GO :0015031 and protein transport and biological process this GO :0016020 and membrane and cellular component this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0017137 and Rab GTPase binding and molecular function this GO :0019003 and GDP binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0030140 and trans- this GO lgi network transport vesicle and cellular component this GO :0030425 and dendrite and cellular component this GO :0030659 and cytoplasmic vesicle membrane and cellular component this GO :0030670 and pha this GO cytic vesicle membrane and cellular component this GO :0031513 and nonmotile primary cilium and cellular component this GO :0032869 and cellular response to insulin stimulus and biological process this GO :0032880 and regulation of protein localization and biological process this GO :0036064 and ciliary basal body and cellular component this GO :0042384 and cilium assembly and biological process this GO :0043025 and neuronal cell body and cellular component this GO :0045335 and pha this GO cytic vesicle and cellular component this GO :0048169 and regulation of long-term neuronal synaptic plasticity and biological process this GO :0048210 and this GO lgi vesicle fusion to target membrane and biological process this GO :0051223 and regulation of protein transport and biological process this GO :0055037 and recycling endosome and cellular component this GO :0055038 and recycling endosome membrane and cellular component this GO :0061024 and membrane organization and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0072659 and protein localization to plasma membrane and biological process, this GO :0003924: GTPase activity, this GO :0003924: GTPase activity and also this GO :0005515: protein binding and also this GO :0005525: GTP binding and also this GO :0017137: Rab GTPase binding and also this GO :0019003: GDP binding and also this GO :0019901: protein kinase binding, this GO :0005515: protein binding, this GO :0005525: GTP binding, this GO :0017137: Rab GTPase binding, this GO :0019003: GDP binding, this GO :0019901: protein kinase binding, RAB8A |
| Identity | 7007 |
| Gene | RAB8A |
| Long gene name | RAB8A, member RAS oncogene family |
| Synonyms gene | MEL |
| Synonyms gene name | mel transforming oncogene (derived from cell line NK14) |
| Synonyms | RAB8 |
| Locus | 19p13, 11 |
| Discovery year | 1986-01-01 |
| Entrez gene record | 4218 |
| Pubmed identfication | 1886711 8408203 |
| RefSeq identity | NM_005370 |
| Classification | RAB, member RAS oncogene GTPases |
| Havana BLAST/BLAT | OTTHUMG00000182238 |
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