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Rad17 (Ser645) Antibody, FITC Conjugated

Rad17 (Ser645) Antibody, FITC Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, Rad17 (Ser645) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRad17 Ser645
SpecificityThis is a highly specific antibody against Rad17 Ser645
ModificationPhosphorylation
Modification siteSer645
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human Rad17 around the phosphorylation site of Ser645
Gene ID number5884
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Jul 2013], Multiple alternatively spliced transcript variants of this gene, The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage, This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, This protein shares strong similarity with DNA replication factor C (RFC), Two pseudogenes, [provided by RefSeq, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage, and can form a complex with RFCs, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells, have been identified, have been reported, located on chromosomes 7 and 13, which encode four distinct protein isoforms, which may be required for its phosphorylation, The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms Cell cycle checkpoint protein, Cell cycle checkpoint protein RAD17, HRAD 17, HRAD17, R24L, RAD1 S, RAD17 homolog, RAD17Sp, RF C activator 1 homolog, RF C/activator 1 homolog, Rad 17, Rad 24, Rad17 like protein, Rad24, pombe homolog, CCYC
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetRad17 (Ser645) Conjugated
Short name FITC Conjugated, Rad17 (Ser645) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, Rad17 (Ser645) (Antibody to)
Alternative techniqueantibodies

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