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RAD21 Antibody

RAD21 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameRAD21 Primary Polyclonal Antibody
Also known asRAD21 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenRAD21
SpecificityThis is a highly specific antibody against RAD21
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range570-620/631
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Rad2
Gene ID number5885
Swiss ProtO60216
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Also plays a role in apoptosis, At metaphase-anaphase transition, The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped, The cohesin complex is required for the cohesion of sister chromatids after DNA replication, The cohesin complex may also play a role in spindle pole assembly during mitosis, allowing sister chromatids to segregate, and in apoptosis, in DNA repair, involved in chromosome cohesion during cell cycle, this protein is cleaved by separase/ESPL1 and dissociates from chromatin, via its cleavage by caspase-3/CASP3 or caspase-7/CASP7 during early steps of apoptosis: the C-terminal 64 kDa cleavage product may act as a nuclear signal to initiate cytoplasmic events involved in the apoptotic pathway, Cleavable component of the cohesin complex
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CDLS4, Double-strand-break repair protein rad21 homolog, HRAD21, KIAA0078, MCD1, NXP-1, NXP1, Nuclear matrix protein 1, RAD21, SCC1, SCC1 homolog, hHR21, HR21
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetRAD21
Short nameRAD21 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name pombe) (Antibody to), RAD21 homolog (S
Alternative techniqueantibodies
Alternative to gene target CDLS4 and hHR21 and HR21 and HRAD21 and MCD1 and NXP1 and SCC1, RAD21 and IDBG-33417 and ENSG00000164754 and 5885, RAD21 and IDBG-644888 and ENSBTAG00000007303 and 540966, Rad21 and IDBG-139998 and ENSMUSG00000022314 and 19357, centromeric region and cellular component this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005694 and chromosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0006302 and double-strand break repair and biological process this GO :0006310 and DNA recombination and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006915 and apoptotic process and biological process this GO :0007059 and chromosome segregation and biological process this GO :0007067 and mitotic nuclear division and biological process this GO :0007131 and reciprocal meiotic recombination and biological process this GO :0008278 and cohesin complex and cellular component this GO :0016020 and membrane and cellular component this GO :0034991 and nuclear meiotic cohesin complex and cellular component this GO :0045087 and innate immune response and biological process this GO :0071168 and protein localization to chromatin and biological process, nuclei, pombe), protein binding, this GO :0000228 and nuclear chromosome and cellular component this GO :0000278 and mitotic cell cycle and biological process this GO :0000775 and chromosome, this GO :0005515: protein binding, this GO :0005515: protein binding, RAD21 homolog (S
Identity 9811
Gene RAD21
Long gene name RAD21 cohesin complex component
Synonyms gene name RAD21 (S, pombe) , pombe) homolog RAD21 homolog (S
Synonyms KIAA0078 hHR21 SCC1
Synonyms name sister chromatid cohesion 1 kleisin
Locus 8q24, 11
Discovery year 1996-06-12
GenBank acession BC050381
Entrez gene record 5885
Pubmed identfication 8812457
RefSeq identity NM_006265
Classification Cohesin complex
Havana BLAST/BLAT OTTHUMG00000164959
Locus Specific Databases LRG_772

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