Name : RAD21 Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN3221696051
| Long name | Cy3 Conjugated, RAD21 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | RAD21 |
| Specificity | This is a highly specific antibody against RAD21 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 570-620/631 |
| Subcellular location | Nucleus |
| Source | KLH conjugated synthetic peptide derived from human Rad2 |
| Gene ID number | 5885 |
| Swiss Prot | O60216 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Also plays a role in apoptosis, At metaphase-anaphase transition, The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped, The cohesin complex is required for the cohesion of sister chromatids after DNA replication, The cohesin complex may also play a role in spindle pole assembly during mitosis, allowing sister chromatids to segregate, and in apoptosis, in DNA repair, involved in chromosome cohesion during cell cycle, this protein is cleaved by separase/ESPL1 and dissociates from chromatin, via its cleavage by caspase-3/CASP3 or caspase-7/CASP7 during early steps of apoptosis: the C-terminal 64 kDa cleavage product may act as a nuclear signal to initiate cytoplasmic events involved in the apoptotic pathway, Cleavable component of the cohesin complex |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Synonyms | KIAA0078 hHR21 SCC1 |
| Properties | 1 of the RAD21 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | RAD21 Conjugated |
| Short name | Conjugated, RAD21 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | cyanine 3 coupled, pombe) (Antibody to), RAD21 homolog (S |
| Alternative technique | antibodies |
| Alternative to gene target | CDLS4 and hHR21 and HR21 and HRAD21 and MCD1 and NXP1 and SCC1, RAD21 and IDBG-33417 and ENSG00000164754 and 5885, RAD21 and IDBG-644888 and ENSBTAG00000007303 and 540966, Rad21 and IDBG-139998 and ENSMUSG00000022314 and 19357, centromeric region and cellular component this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005694 and chromosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0006302 and double-strand break repair and biological process this GO :0006310 and DNA recombination and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006915 and apoptotic process and biological process this GO :0007059 and chromosome segregation and biological process this GO :0007067 and mitotic nuclear division and biological process this GO :0007131 and reciprocal meiotic recombination and biological process this GO :0008278 and cohesin complex and cellular component this GO :0016020 and membrane and cellular component this GO :0034991 and nuclear meiotic cohesin complex and cellular component this GO :0045087 and innate immune response and biological process this GO :0071168 and protein localization to chromatin and biological process, nuclei, pombe), protein binding, this GO :0000228 and nuclear chromosome and cellular component this GO :0000278 and mitotic cell cycle and biological process this GO :0000775 and chromosome, this GO :0005515: protein binding, this GO :0005515: protein binding, RAD21 homolog (S |
| Identity | 9811 |
| Gene | RAD21 |
| Long gene name | RAD21 cohesin complex component |
| Synonyms gene name | RAD21 (S, pombe) , pombe) homolog RAD21 homolog (S |
| Synonyms name | sister chromatid cohesion 1 kleisin |
| Locus | 8q24, 11 |
| Discovery year | 1996-06-12 |
| GenBank acession | BC050381 |
| Entrez gene record | 5885 |
| Pubmed identfication | 8812457 |
| RefSeq identity | NM_006265 |
| Classification | Cohesin complex |
| Havana BLAST/BLAT | OTTHUMG00000164959 |
| Locus Specific Databases | LRG_772 |