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RAD51(Tyr315) Antibody, ALEXA FLUOR 488

RAD51(Tyr315) Antibody, ALEXA FLUOR 488 size: 100ul 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 350
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, RAD51(Tyr315) Polyclonal Antibody
Also known asAnti-RAD51 Tyr315 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRAD51 Tyr315
SpecificityThis is a highly specific antibody against RAD51 Tyr315
ModificationPhosphorylation
Modification SiteTyr315
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human RAD51 around the phosphorylation site of Tyr315
Gene ID Number5888
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein, Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis, RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, This protein can interact with the ssDNA-binding protein RPA and RAD52, This protein is also found to interact with BRCA1 and BRCA2, Transcript variants utilizing alternative polyA signals exist, Two alternatively spliced transcript variants of this gene, and are known to be involved in the homologous recombination and repair of DNA, and it is thought to play roles in homologous pairing and strand transfer of DNA, have been reported, which encode distinct proteins, which may be important for the cellular response to DNA damage, The protein encoded by this gene is a member of the RAD51 protein family
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms HsRad51 HsT16930 BRCC5 FANCR
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the RAD51(Tyr315) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetRAD51(Tyr315)
Short nameRAD51(Tyr315) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, RAD51(Tyr315) (Antibody to)
Alternative techniqueantibodies
Identity 9817
Gene RAD51
Long gene name RAD51 recombinase
Synonyms gene RAD51A RECA
Synonyms gene name E, RAD51 (S, cerevisiae) , cerevisiae) RAD51 homolog (S, cerevisiae) homolog (E coli RecA homolog) RAD51 homolog (RecA homolog, coli) (S
Synonyms name BRCA1/BRCA2-containing complex, subunit 5
Locus 15q15, 1
Discovery year 1993-05-26
GenBank acession D13804
Entrez gene record 5888
Pubmed identfication 8358431 8479919 26253028
RefSeq identity NM_002875 NM_133487
Classification Fanconi anemia complementation groups
Havana BLAST/BLAT OTTHUMG00000130067

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