Name : RAD51(Tyr315) Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :368
SKU : GEN2350942844
| Long name | Cy3 Conjugated, RAD51(Tyr315) Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | RAD51 Tyr315 |
| Specificity | This is a highly specific antibody against RAD51 Tyr315 |
| Modification | Phosphorylation |
| Modification site | Tyr315 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human RAD51 around the phosphorylation site of Tyr315 |
| Gene ID number | 5888 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein, Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis, RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, This protein can interact with the ssDNA-binding protein RPA and RAD52, This protein is also found to interact with BRCA1 and BRCA2, Transcript variants utilizing alternative polyA signals exist, Two alternatively spliced transcript variants of this gene, and are known to be involved in the homologous recombination and repair of DNA, and it is thought to play roles in homologous pairing and strand transfer of DNA, have been reported, which encode distinct proteins, which may be important for the cellular response to DNA damage, The protein encoded by this gene is a member of the RAD51 protein family |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Synonyms | HsRad51 HsT16930 BRCC5 FANCR |
| Properties | 1 of the RAD51(Tyr315) Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | RAD51(Tyr315) Conjugated |
| Short name | Conjugated, RAD51(Tyr315) Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | cyanine 3 coupled, RAD51(Tyr315) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 9817 |
| Gene | RAD51 |
| Long gene name | RAD51 recombinase |
| Synonyms gene | RAD51A RECA |
| Synonyms gene name | E, RAD51 (S, cerevisiae) , cerevisiae) RAD51 homolog (S, cerevisiae) homolog (E coli RecA homolog) RAD51 homolog (RecA homolog, coli) (S |
| Synonyms name | BRCA1/BRCA2-containing complex, subunit 5 |
| Locus | 15q15, 1 |
| Discovery year | 1993-05-26 |
| GenBank acession | D13804 |
| Entrez gene record | 5888 |
| Pubmed identfication | 8358431 8479919 26253028 |
| RefSeq identity | NM_002875 NM_133487 |
| Classification | Fanconi anemia complementation groups |
| Havana BLAST/BLAT | OTTHUMG00000130067 |