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RAD51(Tyr315) Antibody, Cy3 Conjugated

RAD51(Tyr315) Antibody, Cy3 Conjugated size: 0.1ml 368

Price 368
Size 0.1ml
Long name Cy3 Conjugated, RAD51(Tyr315) Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugationcy3 conjugation kit
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRAD51 Tyr315
SpecificityThis is a highly specific antibody against RAD51 Tyr315
ModificationPhosphorylation
Modification siteTyr315
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human RAD51 around the phosphorylation site of Tyr315
Gene ID number5888
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein, Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis, RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, This protein can interact with the ssDNA-binding protein RPA and RAD52, This protein is also found to interact with BRCA1 and BRCA2, Transcript variants utilizing alternative polyA signals exist, Two alternatively spliced transcript variants of this gene, and are known to be involved in the homologous recombination and repair of DNA, and it is thought to play roles in homologous pairing and strand transfer of DNA, have been reported, which encode distinct proteins, which may be important for the cellular response to DNA damage, The protein encoded by this gene is a member of the RAD51 protein family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission512, 550nm/570, 615nm
Synonyms HsRad51 HsT16930 BRCC5 FANCR
Properties 1 of the RAD51(Tyr315) Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetRAD51(Tyr315) Conjugated
Short name Conjugated, RAD51(Tyr315) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy3
Alternative name cyanine 3 coupled, RAD51(Tyr315) (Antibody to)
Alternative techniqueantibodies
Identity 9817
Gene RAD51
Long gene name RAD51 recombinase
Synonyms gene RAD51A RECA
Synonyms gene name E, RAD51 (S, cerevisiae) , cerevisiae) RAD51 homolog (S, cerevisiae) homolog (E coli RecA homolog) RAD51 homolog (RecA homolog, coli) (S
Synonyms name BRCA1/BRCA2-containing complex, subunit 5
Locus 15q15, 1
Discovery year 1993-05-26
GenBank acession D13804
Entrez gene record 5888
Pubmed identfication 8358431 8479919 26253028
RefSeq identity NM_002875 NM_133487
Classification Fanconi anemia complementation groups
Havana BLAST/BLAT OTTHUMG00000130067

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