Name : Rad53/SPK1 Antibody, ALEXA FLUOR 350
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN6359675873
| Long name | ALEXA FLUOR 350 Conjugated, Rad53/SPK1 Polyclonal Antibody |
| Also known as | Anti-Rad53/SPK1 PAb ALEXA FLUOR 350 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 350, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Rad53/SPK1 |
| Specificity | This is a highly specific antibody against Rad53/SPK1 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Rad53/SPK1 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Activation of Rad53 is regulated by Mec1 (also known as Esr1 and Sad3), Checkpoints exist at several cell cycle phase transitions to maintain this genetic integrity, Dun1, Mec2 or Sad1) is essential for both G2 and S phase arrest, Pds1 and Mad2 both regulate checkpoints associated with incomplete spindle replication (7, Pol2 (also known as Dun2), Rad17, Rad24 and Mec3 are involved in activating the G1 and G2 checkpoints (1â, Rad9, The protein kinase Rad53 (also designated Spk1, a homolog of the human ATM protein (6), allowing the damaged DNA to be repaired prior to replication, another protein kinase, encoding the catalytic subunit of DNA polymerase epsilon, plays a role in activating the S phase checkpoint (5), plays a role in transducing the DNA damage signal (9), &euro, &ldquo, 4), 8), DNA damage results in the arrest of cell cycle progression |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 343nm/442nm |
| Synonyms | CHK2 homolog, MEC2, RAD53, RAD53_YEAST, SPK1, Serine protein kinase 1, Serine-protein kinase 1, Serine/threonine-protein kinase RAD53, CHEK2 homolog |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 350, Alexa Fluor |
| Gene target | Rad53/SPK1 |
| Short name | Rad53/SPK1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 350 |
| Alternative name | ALEXA FLUOR 350, Rad53/SPK1 (Antibody to) |
| Alternative technique | antibodies |