Filters

RANK Antibody, ALEXA FLUOR 594

RANK Antibody, ALEXA FLUOR 594 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 594 Conjugated, RANK Polyclonal Antibody
Also known asAnti-RANK PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRANK
SpecificityThis is a highly specific antibody against RANK
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RANK
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen CD265 is also expressed in dendritic cells, CD265 is widely expressed, Human and murine CD265 share 81% amino acid identity in their extracellular domains, Multiple tumor necrosis factor receptor-associated factors (TRAFs) are involved in the signaling of CD265, RANK and RANK ligand (RANKL) are important regulators of interactions between T cells and dendritic cells, RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis, TRANCE (TNF-related activation-induced cytokines, The binding of anti-CD265 to cell surface CD265 triggers signal transduction and induces CD265 mediated bioactivity, The biological functions mediated by RANK include activation of NFkappaB and cjun N-terminal kinase, The soluble form of CD265 is able to block TRANCE induced biological activity, also known as RANK ligand, colon, enhancement of T cell growth and dendritic cell function, induction of osteoclastogenesis and lymph node organogenesis, liver, osteoprotegerin ligand and osteoclast differentiation factor) is the ligand for CD265, small intestine and adrenal gland, thymus, with highest levels in skeletal muscle, CD265 is a member of the tumor necrosis factor receptor (TNFR) family
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms RANK CD265 FEO
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetRANK
Short nameRANK Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, RANK (Antibody to)
Alternative techniqueantibodies
Identity 11908
Gene TNFRSF11A
Long gene name TNF receptor superfamily member 11a
Synonyms gene PDB2 LOH18CR1
Synonyms gene name 18, NFKB activator , activator of NFKB Paget disease of bone 2 loss of heterozygosity, chromosomal region 1 tumor necrosis factor receptor superfamily, member 11a, member 11a, tumor necrosis factor receptor superfamily
Locus 18q21, 33
Discovery year 1998-12-04
GenBank acession AF018253
Entrez gene record 8792
Pubmed identfication 9367155 10615125
Classification CD molecules Tumor necrosis factor receptor superfamily
Havana BLAST/BLAT OTTHUMG00000132779
Locus Specific Databases LRG_194

Similar products

Subscribe to our Newsletter