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RAPGEF5/Repac Antibody

RAPGEF5/Repac Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameRAPGEF5/Repac Primary Polyclonal Antibody
Also known asRAPGEF5/Repac PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenRAPGEF5/Repac
SpecificityThis is a highly specific antibody against RAPGEF5/Repac
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RAPGEF5
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Existing as two alternatively spliced isoforms, Guanine nucleotide exchange factors (GEFs), Repac, The gene that encodes Repac maps to human chromosome 7p15, also known as Rap guanine nucleotide exchange factor 5 (RAPGEF5), is a 580 amino acid protein that is expressed in brain and testis, lung, mouse and rat, pancreas and small intestine, placenta, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation, such as Repac, the Repac gene is conserved in cow, with high expression of this region linking to positive response to erlotinib therapy for those with non-small-cell lung cancer, with weaker expression in heart, 3, Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Guanine nucleotide exchange factor for Rap1, KIAA0277, M Ras regulated Rap GEF, M-Ras-regulated Rap GEF, MR GEF, MR-GEF, MRGEF, RPGF5_HUMAN, Rap guanine nucleotide exchange factor 5, Rapgef5, Related to Epac, Repac, GFR
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetRAPGEF5/Repac
Short nameRAPGEF5/Repac Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRAPGEF5/Repac (Antibody to)
Alternative techniqueantibodies
Identity 16862
Gene RAPGEF5
Long gene name Rap guanine nucleotide exchange factor 5
Synonyms gene name Rap guanine nucleotide exchange factor (GEF) 5
Synonyms KIAA0277 GFR MR-GEF
Synonyms name M-Ras-regulated GEF
Locus 7p15, 3
Discovery year 2004-03-01
GenBank acession D87467
Entrez gene record 9771
Pubmed identfication 9039502 10486569
RefSeq identity NM_012294
Havana BLAST/BLAT OTTHUMG00000152525

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