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RAR alpha Antibody, FITC Conjugated

RAR alpha Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, RAR alpha Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRAR alpha
SpecificityThis is a highly specific antibody against RAR alpha
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range410-462/462
Subcellular location Nucleus, Cytoplasm
SourceOVA conjugated synthetic peptide derived from mouse Retinoic acid Receptor Alpha
Gene ID number19401
Swiss ProtP11416
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Has a role in the survival of early spermatocytes at the beginning prophase of meiosis, In Sertoli cells, In concert with RARG, In the absence of ligand, Mediates retinoic acid-induced granulopoiesis, On ligand binding, RARA plays an essential role in the regulation of retinoic acid-induced germ cell development during spermatogenesis, Regulates expression of target genes in a ligand-dependent manner by recruiting chromatin complexes containing KMT2E/MLL5, Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes, chromatin condensation and transcriptional suppression, matrix homeostasis and growth plate function, may promote the survival and development of early meiotic prophase spermatocytes, required for skeletal growth, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation, Receptor for retinoic acid
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms RAR NR1B1
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetRAR alpha Conjugated
Short name FITC Conjugated, RAR alpha Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, RAR a (Antibody to)
Alternative techniqueantibodies
Identity 9864
Gene RARA
Long gene name retinoic acid receptor alpha
Synonyms gene name alpha , retinoic acid receptor
Locus 17q21, 2
Discovery year 1988-06-09
GenBank acession X06538
Entrez gene record 5914
Pubmed identfication 2825036 8244378
Classification Nuclear hormone receptors
Havana BLAST/BLAT OTTHUMG00000133328
Locus Specific Databases LRG_1070

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