Filters

RASGRF1 (Ser929) Antibody, FITC Conjugated

RASGRF1 (Ser929) Antibody, FITC Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name FITC Conjugated, RASGRF1 (Ser929) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRASGRF1 Ser929
SpecificityThis is a highly specific antibody against RASGRF1 Ser929
ModificationPhosphorylation
Modification siteSer929
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human RasGRF1 around the phosphorylation site of Ser929
Gene ID number5923
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Alternatively spliced transcript variants encoding distinct isoforms have been reported, Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein, Mar 2009], Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory, The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, [provided by RefSeq, and G protein beta-gamma subunit, muscarinic receptors, The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms CDC25L CDC25 GRF55 H-GRF55 GNRP PP13187
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetRASGRF1 (Ser929) Conjugated
Short name FITC Conjugated, RASGRF1 (Ser929) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, Ras protein-specific guanine nucleotide-releasing factor 1 (Ser929) (Antibody to)
Alternative techniqueantibodies
Alternative to gene target CDC25 and CDC25L and GNRP and GRF1 and GRF55 and H-GRF55 and PP13187 and ras-GRF1, Plasma membranes, RASGRF1 and IDBG-25346 and ENSG00000058335 and 5923, RASGRF1 and IDBG-630181 and ENSBTAG00000019940 and 520039, Rasgrf1 and IDBG-190479 and ENSMUSG00000032356 and 19417, glutamate receptor binding, this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005088 and Ras guanyl-nucleotide exchange factor activity and molecular function this GO :0005089 and Rho guanyl-nucleotide exchange factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007165 and signal transduction and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007616 and long-term memory and biological process this GO :0008283 and cell proliferation and biological process this GO :0030426 and growth cone and cellular component this GO :0031175 and neuron projection development and biological process this GO :0032320 and positive regulation of Ras GTPase activity and biological process this GO :0032863 and activation of Rac GTPase activity and biological process this GO :0035020 and regulation of Rac protein signal transduction and biological process this GO :0035023 and regulation of Rho protein signal transduction and biological process this GO :0035254 and glutamate receptor binding and molecular function this GO :0043005 and neuron projection and cellular component this GO :0046578 and regulation of Ras protein signal transduction and biological process this GO :0046579 and positive regulation of Ras protein signal transduction and biological process this GO :0048167 and regulation of synaptic plasticity and biological process this GO :0048168 and regulation of neuronal synaptic plasticity and biological process this GO :0051056 and regulation of small GTPase mediated signal transduction and biological process this GO :2000310 and regulation of N-methyl-D-aspartate selective glutamate receptor activity and biological process, this GO :0005085: guanyl-nucleotide exchange factor activity, this GO :0005085: guanyl-nucleotide exchange factor activity and also this GO :0005088: Ras guanyl-nucleotide exchange factor activity and also this GO :0005089: Rho guanyl-nucleotide exchange factor activity and also this GO :0005515: protein binding and also this GO :0035254: glutamate receptor binding, this GO :0005088: Ras guanyl-nucleotide exchange factor activity, this GO :0005089: Rho guanyl-nucleotide exchange factor activity, this GO :0005515: protein binding, this GO :0035254: glutamate receptor binding, Ras protein-specific guanine nucleotide-releasing factor 1
Identity 9875
Gene RASGRF1
Long gene name Ras protein specific guanine nucleotide releasing factor 1
Synonyms gene GRF1
Locus 15q25, 1
Discovery year 1994-02-11
GenBank acession M91815
Entrez gene record 5923
Pubmed identfication 7684828 1379731
RefSeq identity NM_002891
Classification Rho guanine nucleotide exchange factors Pleckstrin homology domain containing
Havana BLAST/BLAT OTTHUMG00000144172

Subscribe to our Newsletter