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RASSF1 Antibody

RASSF1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameRASSF1 Primary Polyclonal Antibody
Also known asRASSF1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenRASSF1
SpecificityThis is a highly specific antibody against RASSF1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range150-195/340
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RASSF1
Gene ID number11186
Swiss ProtQ9NS23
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen APC, DAXX and USP7, Inhibits proliferation by negatively regulating cell cycle progression at the level of G1/S-phase transition by regulating accumulation of cyclin D1 protein, Isoform A disrupts interactions among MDM2, Isoform A interacts with CDC2, Isoform C has been shown not to perform these roles, Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation, Required for death receptor-dependent apoptosis, When associated with MOAP1, an activator of the anaphase-promoting complex, no function has been identified for this isoform, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF1 stimulation, resulting in the inhibition of APC activity and mitotic progression, thus contributing to the efficient activation of TP53 by promoting MDM2 self-ubiquitination in cell-cycle checkpoint control in response to DNA damage, Potential tumor suppressor
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names NORE2A, RASSF1, RASSF1A, RDA32, REH3P21, Ras association domain-containing protein 1, 123F2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetRASSF1
Short nameRASSF1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRASSF1 (Antibody to)
Alternative techniqueantibodies
Identity 9882
Gene RASSF1
Long gene name Ras association domain family member 1
Synonyms gene name Ras association (RalGDS/AF-6) domain family member 1
Synonyms NORE2A REH3P21 RDA32 123F2
Locus 3p21, 31
Discovery year 2000-05-30
GenBank acession AF132675
Entrez gene record 11186
Classification Ras association domain family
Havana BLAST/BLAT OTTHUMG00000149958

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