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RASSF1 Antibody, FITC Conjugated

RASSF1 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, RASSF1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRASSF1
SpecificityThis is a highly specific antibody against RASSF1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range150-195/340
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human RASSF1
Gene ID number11186
Swiss ProtQ9NS23
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background APC, DAXX and USP7, Inhibits proliferation by negatively regulating cell cycle progression at the level of G1/S-phase transition by regulating accumulation of cyclin D1 protein, Isoform A disrupts interactions among MDM2, Isoform A interacts with CDC2, Isoform C has been shown not to perform these roles, Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation, Required for death receptor-dependent apoptosis, When associated with MOAP1, an activator of the anaphase-promoting complex, no function has been identified for this isoform, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF1 stimulation, resulting in the inhibition of APC activity and mitotic progression, thus contributing to the efficient activation of TP53 by promoting MDM2 self-ubiquitination in cell-cycle checkpoint control in response to DNA damage, Potential tumor suppressor
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms NORE2A REH3P21 RDA32 123F2
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetRASSF1 Conjugated
Short name FITC Conjugated, RASSF1 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, RASSF1 (Antibody to)
Alternative techniqueantibodies
Identity 9882
Gene RASSF1
Long gene name Ras association domain family member 1
Synonyms gene name Ras association (RalGDS/AF-6) domain family member 1
Locus 3p21, 31
Discovery year 2000-05-30
GenBank acession AF132675
Entrez gene record 11186
Classification Ras association domain family
Havana BLAST/BLAT OTTHUMG00000149958

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