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RAT ANTI HUMAN CD49f Antibody

RAT ANTI HUMAN CD49f Antibody size: 200ug 503

Supplier MBS MONO
Price 503
Size 200ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD49f
Other names CD49 antigen-like family member F, CD49 antigen-like family member F, Integrin alpha-6, VLA-6, alpha 6, integrin, integrin alpha-6, integrin alpha6B, integrin alpha-6 isoform b
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD49f
Gene name synonimsN/A
Other gene names CD49f, ITGA6, ITGA6B, N/A, VLA-6, ITGA6
ClonalityMonoclonal
Immunoglobulin isotypeIgG2a
CloneNKI-GoH3
Host organismRat (Rattus norvegicus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity Clone NKI-GoH3 reacts with platelets, In immunohistology the monoclonal antibody reacts with epithelial cells of a variety of tissues, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, Studies suggest that clone NKI-GoH3 specifically blocks the binding of cells to the E8 fragment of laminin, T lymphocytes and common Acute Lymphoblastic Leukaemia cells (alpha-6 beta-1), This particular antibody might cross react with speacies outside of the listed ones, a 120kD cell surface glycoprotein that can form distinct complexes with CD29 (VLA beta-chain), megakaryocytes, microvascular endothelial cells, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells, peripheral nerves, placenta cyto- and syncytotrophoblasts, resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, CD49f This item recognises CD49F (VLA-6 alpha chain), VLA-6 is an important mediator of cell binding to laminin
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0 mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistology - Frozen (IHC)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetCD49f
Short nameRAT ANTI HUMAN CD49f Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens CD49f (Antibody to), RAT antibody to H
Alternative techniqueantibodies
Identity 6142
Gene ITGA6
Long gene name integrin subunit alpha 6
Synonyms gene name alpha 6 , integrin
Synonyms CD49f
Locus 2q31, 1
Discovery year 1991-08-06
Classification Integrin alpha subunits CD molecules
Havana BLAST/BLAT OTTHUMG00000132277

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