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RAT ANTI MOUSE CD123 Antibody

RAT ANTI MOUSE CD123 Antibody size: 0.25 miligrams 437

Supplier MBS MONO
Price 437
Size 0.25 miligrams
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD123
Other names IL-3 receptor alpha SP2 isoform, IL-3 receptor alpha chain, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R-alpha, IL-3RA, Il-3 alpha subunit, Interleukin-3 receptor class II alpha chain, Interleukin-3 receptor subunit alpha, alpha chain, interleukin 3 receptor, interleukin-3 receptor class II alpha chain, interleukin-3 receptor subunit alpha, interleukin-3 receptor subunit alpha
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD123
Gene name synonimsN/A
Other gene names CD123, CDw123, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R-alpha, IL-3RA, Il3ra, SUT-1, Sut-1, Il3ra
ClonalityMonoclonal
Immunoglobulin isotypeIgG2a
Clone5B11
Host organismRat (Rattus norvegicus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus)
Specificity and cross-reactivity AKR/J and NZB/B1NJ are reported to have low levels of CD123 expression due to aberrant splicing of the IL-3R alpha subunit gene, Binding of IL-3 to the IL-3 receptor complex induces the proliferation and differentiation of haematopoietic cells, CD123 can associate with either the common beta subunit CDw131 or with the murine IL-3 beta subunit to form a high affinity receptor for IL-3, CD123 is expressed on haematopoietic progenitors and most myeloid cells including basophils and mast cells, Certain mouse strains including A/J, IL-3 can bind to CD123 itself but with low affinity, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Clone 5B11 does not block the binding of IL-3 to the high affinity IL-3 receptor, _x000D__x000D_In mouse, which is the 70kD alpha chain of the interleukin-3 receptor (IL-3R), CD123 This item recognises murine CD123
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0 mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: Immunofluorescence (IF), Flow Cytometry (FACS)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetCD123
Short nameRAT ANTI MOUSE CD123 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRAT antibody to MOUSE CD123 (Antibody to)
Alternative techniqueantibodies
Identity 6012
Gene IL3RA
Long gene name interleukin 3 receptor subunit alpha
Synonyms gene name alpha (low affinity) , interleukin 3 receptor
Synonyms CD123
Locus Xp22, 3 , 3 and Yp13
Discovery year 1992-10-28
GenBank acession M74782
Entrez gene record 3563
Pubmed identfication 1833064
Classification CD molecules Pseudoautosomal region 1 Interleukin receptors
Havana BLAST/BLAT OTTHUMG00000021059

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