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RAT ANTI MOUSE CD18:Biotin Antibody

RAT ANTI MOUSE CD18:Biotin Antibody size: 100ug 337

Supplier MBS MONO
Price 337
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD18
Other names Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement receptor C3 subunit beta, Integrin beta-2, Mac-1 beta, cell surface adhesion glycoproteins LFA-1/CR3/p150, complement receptor C3 subunit beta, integrin beta 2, integrin beta-2, lymphocyte function associated antigen 1, macrophage antigen-1 beta, 95 subunit beta, 95 subunit beta, integrin beta-2
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD18
Gene name synonimsN/A
Other gene names 2E6, AI528527, Cd18, Itgb2, LAD, LCAMB, Lfa1, MF17, N/A, Itgb2
ClonalityMonoclonal
Immunoglobulin isotypeIgG2a
CloneM18/2
Host organismRat (Rattus norvegicus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus)
Specificity and cross-reactivity CD11b/CD18 and CD11c/CD18 respectively, CD18 is a 95KD cell surface glycoprotein that forms heterodimers with the integrin subunit alpha L (CD11a), CD18 is expressed by all leucocytes and plays an important role in adhesion and signalling in the haematopoietic system, Clone M18/2 has been reported to both inhibit and enhance certain functions of CD18 (please refer to references 2 and 3), Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, alpha M (CD11b) or alpha X (CD11c) to produce integrins CD11a/CD18, CD18 This item recognises the murine beta 2 integrin (CD18)
Purification methodN/A
Form/AppearanceBiotin (Purified IgG conjugated to Biotin - liquid)
Concentration1 miligram per 1 mililiter, IgG concentration 0
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications:Flow Cytometry (FACS)
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
ConjugationBiotinylated
Gene targetCD18:
Short nameRAT ANTI MOUSE CD18: Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelBiotin
Alternative nameRAT antibody to MOUSE CD18:biotinilated (Antibody to)
Alternative techniqueantibodies
Identity 6155
Gene ITGB2
Long gene name integrin subunit beta 2
Synonyms gene CD18 MFI7
Synonyms gene name beta 2 (antigen CD18 (p95), beta 2 (complement component 3 receptor 3 and 4 subunit) , integrin, lymphocyte function-associated antigen 1, macrophage antigen 1 (mac-1) beta subunit) integrin
Synonyms LFA-1 MAC-1
Synonyms name complement component 3 receptor 3 and 4 subunit
Locus 21q22, 3
Discovery year 1986-01-01
GenBank acession AK222505
Entrez gene record 3689
RefSeq identity NM_000211
Classification Complement system Integrin beta subunits CD molecules
Havana BLAST/BLAT OTTHUMG00000090257
Locus Specific Databases ITGB2base: Mutation registry for Leukocyte adhesion deficiency I (LAD-I) LRG_76

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