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RAT ANTI MOUSE CD223:RPE Antibody

RAT ANTI MOUSE CD223:RPE Antibody size: 100 Tests 299

Supplier MBS MONO
Price 299
Size 100 Tests
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD223
Other names Lymphocyte activation gene 3 protein, N/A, lymphocyte activation gene 3 protein, lymphocyte-activation gene 3, lymphocyte activation gene 3 protein
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD223
Gene name synonimsN/A
Other gene names CD223, LAG-3, LAG-3, Lag3, Ly66, Lag3
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
CloneC9B7W
Host organismRat (Rattus norvegicus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus)
Specificity and cross-reactivity CD223 binds to MHC class II molecules with high affinity and is reported to negatively regulate T cell homeostasis and T cell expansion, Clone C9B7W recognises an epitope within the D2 domain of CD223, Murine CD223 is expressed on activated CD4 positive and CD8 positive alpha/beta T lymphocytes and a subset of natural killer (NK) cells, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The antibody is reported to block the <, This particular antibody might cross react with speacies outside of the listed ones, a 70kD activation-induced cell surface molecule that is also referred to as CD223, function of murine LAG-3 but studies suggest that the antibody does not block binding of LAG-3 to MHC class II , /I>, CD223 This item recognises murine lymphocyte activation gene-3 (LAG-3), I>, in vitro<
Purification methodN/A
Form/Appearance Phycoerythrin (RPE) - lyophilised), RPE (Purified IgG conjugated to R
ConcentrationN/A
Storage and shipping After reconstitution Keep the antibody refrigerated at +4 degrees Celsius, DO NOT FREEZE, If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Shelf Life: 12 months from date of reconstitution, Temperature variations in the range between +1C to +7C are tolerable, Temperature variations in the range between +1C to +7C are tolerable, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Prior to reconstitution Keep the antibody refrigerated at +4 degrees Celsius
Tested applications:Flow Cytometry (FACS)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetCD223:RPE
Short nameRAT ANTI MOUSE CD223:RPE Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRAT antibody to MOUSE CD223:RPE (Antibody to)
Alternative techniqueantibodies
Identity 6476
Gene LAG3
Long gene name lymphocyte activating 3
Synonyms gene name lymphocyte-activation gene 3
Synonyms CD223
Locus 12p13, 31
Discovery year 1991-06-03
Entrez gene record 3902
RefSeq identity NM_002286
Classification CD molecules Immunoglobulin like domain containing
Havana BLAST/BLAT OTTHUMG00000169197

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