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RAT ANTI MOUSE CD273:FITC Antibody

RAT ANTI MOUSE CD273:FITC Antibody size: 100ug 277

Supplier MBS MONO
Price 277
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD273
Other names Butyrophilin B7-DC, PD-1 ligand 2, PDCD1 ligand 2, Programmed cell death 1 ligand 2, butyrophilin B7-DC, butyrophilin-like protein, programmed cell death 1 ligand 2, programmed cell death 1 ligand 2, programmed death ligand 2, programmed cell death 1 ligand 2
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD273
Gene name synonimsN/A
Other gene names B7-DC, B7-DC, B7dc, Btdc, Btdc, Cd273, F730015O22Rik, PD-1 ligand 2, PD-L2, PD-L2, PDCD1 ligand 2, Pdcd1lg2, Pdl2, Programmed death ligand 2, Pdcd1lg2
ClonalityMonoclonal
Immunoglobulin isotypeIgG2a
CloneTY25
Host organismRat (Rattus norvegicus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus)
Specificity and cross-reactivity Antibodies produced by clone TY25 are reported to block the binding of CD273 (B7-DC) to it's receptor, CD273 has been identified as a ligand for PD-1(CD279), GM-CSF or IL-4, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, Studies suggest that both CD273 and B7-H1 co-stimulate or inhibit T cell proliferation and cytokine production, The expression of CD273 is restricted to a subpopulation of dendritic cells (DCs), This particular antibody might cross react with speacies outside of the listed ones, a 42kD member of the B7 family, along with another B7 family member B7-H1 (CD274), and DCs and macrophages that have been stimulated with interferon gamma, or programmed death ligand-2 (PD-L2), otherwise known as B7-dendritic cell (B7-DC), CD273 This item recognises mouse CD273
Purification methodN/A
Form/AppearanceFITC (Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid)
Concentration1 miligram per 1 mililiter, IgG concentration 0
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications:Flow Cytometry (FACS)
Properties FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
ConjugationAnti-FITC Antibody
Gene targetCD273:
Short nameRAT ANTI MOUSE CD273:FITC Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, Antibody
LabelFITC
Alternative nameRAT antibody to MOUSE CD273:fluorecein (Antibody to)
Alternative techniqueantibodies
Identity 18731
Gene PDCD1LG2
Long gene name programmed cell death 1 ligand 2
Synonyms PD-L2 Btdc PDL2 bA574F11, 2 CD273 B7-DC
Synonyms name B7 dendritic cell molecule
Locus 9p24, 1
Discovery year 2003-11-14
GenBank acession AF344424
Entrez gene record 80380
Pubmed identfication 11224527
RefSeq identity NM_025239
Classification Endogenous ligands CD molecules Immunoglobulin like domain containing
Havana BLAST/BLAT OTTHUMG00000019504

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