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RAT ANTI MOUSE CD276:RPE Antibody

RAT ANTI MOUSE CD276:RPE Antibody size: 100 Tests 580

Supplier MBS MONO
Price 580
Size 100 Tests
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD276
Other names B7 homolog 3, B7 homolog 3, B7-H3, B7-H3, CD276 antigen, CD276 antigen, CD276 antigen, Costimulatory molecule, costimulatory molecule, CD276 antigen
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD276
Gene name synonimsN/A
Other gene names 6030411F23Rik, AU016588, B7-H3, B7RP-2, B7h3, B7h3, Cd276, Cd276
ClonalityMonoclonal
Immunoglobulin isotypeIgG2b
CloneMJ8
Host organismRat (Rattus norvegicus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus)
Specificity and cross-reactivity CD276 has been implicated in the development of acute and chronic transplant rejection, CD276 has been linked with the development of pathogenic Th2 cells during the induction phase of allergic asthma, CD276 is highly expressed in bone during embryogenesis, In mice, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, a ubiquitously expressed transmembrane glycoprotein and member of the B7 family of co-stimulatory molecules, and can be induced on dendritic cells and monocytes by inflammatory cytokines, and is reported to have therapeutic potential as a regulator of cell-mediated immune responses to cancer, otherwise known as B7-H3, particularly in conjunction with anti-angiogenic therapy, which acts as both a positive and negative regulator of T-cell-mediated immune responses, CD276 This item specifically recognises mouse CD276
Purification methodN/A
Form/Appearance Phycoerythrin (RPE) - lyophilised), RPE (Purified IgG conjugated to R
ConcentrationN/A
Storage and shipping After reconstitution Keep the antibody refrigerated at +4 degrees Celsius, DO NOT FREEZE, If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Shelf Life: 12 months from date of reconstitution, Temperature variations in the range between +1C to +7C are tolerable, Temperature variations in the range between +1C to +7C are tolerable, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Prior to reconstitution Keep the antibody refrigerated at +4 degrees Celsius
Tested applications:Flow Cytometry (FACS)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetCD276:RPE
Short nameRAT ANTI MOUSE CD276:RPE Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRAT antibody to MOUSE CD276 molecule:RPE (Antibody to)
Alternative techniqueantibodies
Alternative to gene target CD276 and IDBG-21197 and ENSG00000103855 and 80381, CD276 and IDBG-645646 and ENSBTAG00000019734 and 508656, Cd276 and IDBG-172080 and ENSMUSG00000035914 and 102657, Cell surfaces, protein binding, this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0006955 and immune response and biological process this GO :0008283 and cell proliferation and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030501 and positive regulation of bone mineralization and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042110 and T cell activation and biological process this GO :0042130 and negative regulation of T cell proliferation and biological process this GO :0045077 and negative regulation of interferon-gamma biosynthetic process and biological process this GO :0045078 and positive regulation of interferon-gamma biosynthetic process and biological process this GO :0045085 and negative regulation of interleukin-2 biosynthetic process and biological process this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0050776 and regulation of immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :1900042 and positive regulation of interleukin-2 secretion and biological process, this GO :0005102: receptor binding, this GO :0005102: receptor binding and also this GO :0005515: protein binding, this GO :0005515: protein binding, CD276 molecule
Identity 19137
Gene CD276
Long gene name CD276 molecule
Synonyms gene name CD276 antigen
Synonyms B7-H3 B7H3 B7RP-2
Locus 15q24, 1
Discovery year 2005-03-04
GenBank acession AF302102
Entrez gene record 80381
Pubmed identfication 11224528 12055244
RefSeq identity NM_025240
Classification C2-set domain containing CD molecules V-set domain containing
Havana BLAST/BLAT OTTHUMG00000137585

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