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RAT ANTI MOUSE CD279 Antibody

RAT ANTI MOUSE CD279 Antibody size: 0.25 miligrams 437

Supplier MBS MONO
Price 437
Size 0.25 miligrams
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD279
Other names N/A, Programmed cell death protein 1, mPD-1, programmed cell death 1, programmed cell death protein 1, protein PD-1, programmed cell death protein 1
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD279
Gene name synonimsN/A
Other gene names Ly101, PD-1, Pd1, Pdc1, Pdcd1, Protein PD-1, mPD-1, Pdcd1
ClonalityMonoclonal
Immunoglobulin isotypeIgG2b
CloneRMP1-30
Host organismRat (Rattus norvegicus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus)
Specificity and cross-reactivity B7-H1 (PD-L1) and B7-DC (PD-L2), CD279 is expressed predominantly on activated T- and B- lymphocytes and on a subset of thymocytes, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Two members of the B7 family, _x000D__x000D_Antibodies produced by clone RMP1-30 do not block the binding of both B7-H1-Ig and B7-DC-Ig fusion proteins to PD-1 transfected BHK cells, _x000D__x000D_Studies suggest that CD279, a 55kD cell surface protein which is a member of the CD28/CTLA-4 family, an immunoinhibitory receptor, have been identified as the ligands for CD279, otherwise known as Programmed Death-1 (PD-1), plays a critical role in peripheral tolerance induction and prevention of autoimmune disease, CD279 This item recognises mouse CD279
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0 mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications:Flow Cytometry (FACS)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetCD279
Short nameRAT ANTI MOUSE CD279 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRAT antibody to MOUSE CD279 (Antibody to)
Alternative techniqueantibodies
Identity 8760
Gene PDCD1
Long gene name programmed cell death 1
Synonyms gene SLEB2
Synonyms gene name systemic lupus erythematosus susceptibility 2
Synonyms CD279 PD1 hSLE1 PD-1
Locus 2q37, 3
Discovery year 1994-05-24
GenBank acession AY206416
Entrez gene record 5133
Pubmed identfication 7851902 12402038
RefSeq identity NM_005018
Classification CD molecules V-set domain containing
Havana BLAST/BLAT OTTHUMG00000151342

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