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RAT ANTI MOUSE CD357:RPE Antibody

RAT ANTI MOUSE CD357:RPE Antibody size: 100 Tests 420

Supplier MBS MONO
Price 420
Size 100 Tests
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD357
Other names Glucocorticoid-induced TNFR-related protein, Tumor necrosis factor receptor superfamily member 18, glucocorticoid-induced TNFR-related protein, member 18, tumor necrosis factor receptor superfamily, tumor necrosis factor receptor superfamily member 18, tumor necrosis factor receptor superfamily member 18 isoform 1
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD357
Gene name synonimsN/A
Other gene names AITR, Gitr, Gitr, Tnfrsf18, Tnfrsf18
ClonalityMonoclonal
Immunoglobulin isotypeIgG2b
CloneYGITR765
Host organismRat (Rattus norvegicus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus)
Specificity and cross-reactivity CD357 signalling can also enhance the proliferation of naï, Mouse CD357 is predominantly expressed by CD4+/CD25+ T regulatory cells and on CD4+/CD25- cells upon activation, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, Studies demonstrate that mouse GITR ligand (mGITRL) can bind to CD357 and neutralise the suppressive effects of CD4+CD25+ regulatory T cells, This particular antibody might cross react with speacies outside of the listed ones, a member of the tumour necrosis superfamily, also known as glucocorticoid-induced tumour necrosis factor receptor (mGITR) or Tnrfsf18, suggesting a key role for CD357 in the regulation of T cell-mediated immunity, CD357 This product recognises mouse CD357, ve and primed T cells
Purification methodN/A
Form/Appearance Phycoerythrin (RPE) - lyophilised), RPE (Purified IgG conjugated to R
ConcentrationN/A
Storage and shipping DO NOT FREEZE, If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Shelf Life: 12 months from date of reconstitution, Temperature variations in the range between +1C to +7C are tolerable, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Keep the antibody refrigerated at +4 degrees Celsius
Tested applications:Flow Cytometry (FACS)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetCD357:RPE
Short nameRAT ANTI MOUSE CD357:RPE Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRAT antibody to MOUSE CD357:RPE (Antibody to)
Alternative techniqueantibodies
Identity 11914
Gene TNFRSF18
Long gene name TNF receptor superfamily member 18
Synonyms gene name member 18 , tumor necrosis factor receptor superfamily
Synonyms AITR GITR CD357
Locus 1p36, 33
Discovery year 1998-12-04
GenBank acession AF125304
Entrez gene record 8784
Pubmed identfication 9177197 10037686
RefSeq identity NM_004195
Classification CD molecules Tumor necrosis factor receptor superfamily
Havana BLAST/BLAT OTTHUMG00000001414

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