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RAT ANTI MOUSE CD70:Biotin Antibody

RAT ANTI MOUSE CD70:Biotin Antibody size: 100ug 277

Supplier MBS MONO
Price 277
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD70
Other names CD27 ligand, CD27 ligand, CD27-L, CD27-L, CD70 antigen, CD70 antigen, CD70 antigen, Ki-24 antigen, Tumor necrosis factor ligand superfamily member 7, member 7, tumor necrosis factor (ligand) superfamily, tumor necrosis factor ligand superfamily member 7, CD70 antigen
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD70
Gene name synonimsN/A
Other gene names CD27-L, CD27LG, Cd27l, Cd27l, Cd27lg, Cd70, Tnfsf7, Tnfsf7, Cd70
ClonalityMonoclonal
Immunoglobulin isotypeIgG2b
CloneFR70
Host organismRat (Rattus norvegicus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus)
Specificity and cross-reactivity CD70 is not expressed on resting T and B lymphocytes but expression is induced on activation, Clone FR70 is reported to block the functions of CD70 and has been used to block the interactions between CD27 and CD70 , Interaction of CD70 with its ligand CD27 is reported to play an important role in T-cell co-stimulation and the regulation of T-dependant B-cell activation and antibody production, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, a 30-33kD type II transmembrane protein belonging to the TNF superfamily, CD70 This item recognises mouse CD70
Purification methodN/A
Form/AppearanceBiotin (Purified IgG conjugated to Biotin - liquid)
Concentration1 miligram per 1 mililiter, IgG concentration 0
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications:Flow Cytometry (FACS)
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
ConjugationBiotinylated
Gene targetCD70:
Short nameRAT ANTI MOUSE CD70: Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelBiotin
Alternative nameRAT antibody to MOUSE CD70 molecule:biotinilated (Antibody to)
Alternative techniqueantibodies
Alternative to gene target CD27L and CD27LG and TNFSF7, CD70 and IDBG-21699 and ENSG00000125726 and 970, CD70 and IDBG-643945 and ENSBTAG00000009752 and 522074, Cd70 and IDBG-193725 and ENSMUSG00000019489 and 21948, Extracellular, protein binding, this GO :0002020 and protease binding and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005125 and cytokine activity and molecular function this GO :0005164 and tumor necrosis factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008283 and cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0097191 and extrinsic apoptotic signaling pathway and biological process, this GO :0002020: protease binding, this GO :0002020: protease binding and also this GO :0005102: receptor binding and also this GO :0005125: cytokine activity and also this GO :0005164: tumor necrosis factor receptor binding and also this GO :0005515: protein binding, this GO :0005102: receptor binding, this GO :0005125: cytokine activity, this GO :0005164: tumor necrosis factor receptor binding, this GO :0005515: protein binding, CD70 molecule
Identity 11937
Gene CD70
Long gene name CD70 molecule
Synonyms gene CD27LG TNFSF7
Synonyms gene name member 7 , tumor necrosis factor (ligand) superfamily
Synonyms CD27L
Locus 19p13, 3
Discovery year 1993-11-08
GenBank acession L08096
Entrez gene record 970
Pubmed identfication 8387892 8120384
Classification Tumor necrosis factor superfamily CD molecules
Havana BLAST/BLAT OTTHUMG00000181834

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