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RAT ANTI MOUSE CD83:FITC Antibody

RAT ANTI MOUSE CD83:FITC Antibody size: 100ug 365

Supplier MBS MONO
Price 365
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD83
Other names CD83 antigen, CD83 antigen, CD83 antigen, N/A, mCD83, CD83 antigen
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD83
Gene name synonimsN/A
Other gene names Cd83, N/A, mCD83, Cd83
ClonalityMonoclonal
Immunoglobulin isotypeIgG2a
Clone3D11
Host organismRat (Rattus norvegicus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus)
Specificity and cross-reactivity Activated dendritic cells and B-cells release a soluble form of CD83 that is reported to have an immunosuppressive effect, B-cell function and peripheral T-cell activation, CD83 plays a role in the regulation of antigen presentation, Originally described as a maturation marker for dendritic cells, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, a 45kD type 1 glyoprotein belonging to the immunoglobulin superfamily, suggesting a therapeutic role for sCD83 in the regulation of immune disorders, thymic T-cell maturation, CD83 This item recognises murine CD83
Purification methodN/A
Form/AppearanceFITC (Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid)
Concentration1 miligram per 1 mililiter, IgG concentration 0
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from the date of dispatch, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications:Flow Cytometry (FACS)
Properties FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
ConjugationAnti-FITC Antibody
Gene targetCD83:
Short nameRAT ANTI MOUSE CD83:FITC Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, Antibody
LabelFITC
Alternative nameRAT antibody to MOUSE CD83 molecule:fluorecein (Antibody to)
Alternative techniqueantibodies
Alternative to gene target BL11 and HB15, CD83 and IDBG-62750 and ENSG00000112149 and 9308, CD83 and IDBG-636028 and ENSBTAG00000031430 and 617034, Cd83 and IDBG-147707 and ENSMUSG00000015396 and 12522, Cell surfaces, alpha-beta T cell differentiation and biological process, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006952 and defense response and biological process this GO :0006959 and humoral immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0014070 and response to organic cyclic compound and biological process this GO :0032713 and negative regulation of interleukin-4 production and biological process this GO :0032733 and positive regulation of interleukin-10 production and biological process this GO :0032743 and positive regulation of interleukin-2 production and biological process this GO :0043372 and positive regulation of CD4-positive, this GO :0005515: protein binding, this GO :0005515: protein binding, CD83 molecule
Identity 1703
Gene CD83
Long gene name CD83 molecule
Synonyms gene name CD83 antigen (activated B lymphocytes, immunoglobulin superfamily) CD83 molecule
Synonyms HB15 BL11
Locus 6p23
Discovery year 1999-03-26
GenBank acession Z11697
Entrez gene record 9308
Pubmed identfication 1378080 8422464
Classification CD molecules V-set domain containing
Havana BLAST/BLAT OTTHUMG00000014283

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