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RAT ANTI MOUSE DECTIN-1 Antibody

RAT ANTI MOUSE DECTIN-1 Antibody size: 0.25 miligrams 509

Supplier MBS MONO
Price 509
Size 0.25 miligrams
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asDECTIN-1
Other names Beta-glucan receptor, C-type (calcium dependent, C-type lectin domain family 7, C-type lectin domain family 7 member A, C-type lectin domain family 7 member A, C-type lectin superfamily member 12, C-type lectin superfamily member 12, DC-associated C-type lectin 1, Dendritic cell-associated C-type lectin 1, beta-glucan receptor, carbohydrate recognition domain) lectin, dectin-1, dendritic cell-associated C-type lectin 1, member a, superfamily member 12, C-type lectin domain family 7 member A
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene name BGR, Bgr, Clec7a, Clecsf12, Clecsf12, DC-associated C-type lectin 1, Dectin-1, Dectin1, beta-GR, Clec7a
Gene name synonims BGR, Bgr, Clec7a, Clecsf12, Clecsf12, DC-associated C-type lectin 1, Dectin-1, Dectin1, beta-GR, Clec7a
Other gene names BGR, Bgr, Clec7a, Clecsf12, Clecsf12, DC-associated C-type lectin 1, Dectin-1, Dectin1, beta-GR, Clec7a
ClonalityMonoclonal
Immunoglobulin isotypeIgG2b
Clone2A11
Host organismRat (Rattus norvegicus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus)
Specificity and cross-reactivity Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_As a major leucocyte receptor for beta-glucan this molecule may have a key role in the immunomodulatory effects of beta-glucans and in the host response to fungal pathogens, _x000D__x000D_Recent work has shown that Dectin-1 may stimulate reactive oxygen production in macropahges via the protein tyrosine kinase known as Syk, _x000D__x000D_This antibody inhibits the binding of zymosan to macrophages via the beta-glucan receptor, also known as Dectin-1, but also at lower levels by dendritic cells and a subpopulation of T cells, DECTIN-1 This item recognises murine beta-glucan receptor, _x000D_Dectin-1 is predominantly expressed by cells of the monocyte/macrophage and neutrophil lineages
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0 mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: Flow Cytometry (FACS), Immunohistology - Frozen (IHC), Immunoprecipitation (IP)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetDECTIN-1
Short nameRAT ANTI MOUSE DECTIN-1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRAT antibody to MOUSE DECTIN-1 (Antibody to)
Alternative techniqueantibodies
Identity 14558
Gene CLEC7A
Long gene name C-type lectin domain family 7 member A
Synonyms gene CLECSF12
Synonyms gene name C-type (calcium dependent, carbohydrate-recognition domain) lectin, member A , superfamily member 12 C-type lectin domain family 7
Synonyms dectin-1 hDectin-1 CD369 SCARE2
Locus 12p13, 2
Discovery year 2001-02-01
GenBank acession AY009090
Entrez gene record 64581
RefSeq identity NM_197954
Classification CD molecules Scavenger receptors C-type lectin domain family
Havana BLAST/BLAT OTTHUMG00000133597
Locus Specific Databases LRG_179

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