Name : RAT ANTI MOUSE F4/80:RPE Antibody
Supplier : MBS MONO
Price :580
SKU : GEN3286129989
| Also known as | F4/80 |
| Other names | Cell surface glycoprotein F4/80, EGF-like module containing, EGF-like module receptor 1, EGF-like module receptor 1, EGF-like module-containing mucin-like hormone receptor-like 1, EGF-like module-containing mucin-like hormone receptor-like 1, EMR1 hormone receptor, EMR1 hormone receptor, cell surface glycoprotein F4/80, hormone receptor-like sequence 1, lymphocyte antigen 71, mucin-like, EGF-like module-containing mucin-like hormone receptor-like 1 |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | F4/80 |
| Gene name synonims | N/A |
| Other gene names | DD7A5-7, EGF-TM7, Emr1, F4/80, Gpf480, Gpf480, Ly71, TM7LN3, Emr1 |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG2b |
| Clone | Cl:A3-1 |
| Host organism | Rat (Rattus norvegicus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity | Clone Cl:A3-1 has been reported to modulate cytokine levels released in response to <, Expression of F4/80 is heterogeneous and is reported to vary during macrophage maturation and activation, F4/80 expression has also been reported on a subpopulation of dendritic cells but is absent from macrophages located in T cell areas of the spleen and lymph node, Langerhans, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The F4/80 antigen is expressed on a wide range of mature tissue macrophages including Kupffer cells, The ligands and biological functions of the F4/80 antigen have not yet been determined but recent studies suggest a role for F4/80 in the generation of efferent CD8+ve regulatory T cells, This particular antibody might cross react with speacies outside of the listed ones, a 160 kD cell surface glycoprotein that is a member of the EGF-TM7 family of proteins which shares 68% overall amino acid identity with human EGF module-containing mucin-like hormone receptor 1 (EMR1), bone marrow stroma and macrophages in the red pulp of the spleen, lung, macrophages located in the gut lamina propria, microglia, peritoneal cavity, thymus, /I>, F4/80 The F4/80 antibody recognises the murine F4/80 antigen, I>, Listeria monocytogenes< |
| Purification method | N/A |
| Form/Appearance | Phycoerythrin (RPE) - lyophilised), RPE (Purified IgG conjugated to R |
| Concentration | N/A |
| Storage and shipping | DO NOT FREEZE, Following reconstitution Keep the antibody refrigerated at +4 degrees Celsius, If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Shelf Life: 12 months from date of reconstitution, Temperature variations in the range between +1C to +7C are tolerable, Temperature variations in the range between +1C to +7C are tolerable, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Prior to reconstitution Keep the antibody refrigerated at +4 degrees Celsius |
| Tested applications: | Flow Cytometry (FACS), Immunofluorescence (IF) |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target | F4/80:RPE |
| Short name | RAT ANTI MOUSE F4/80:RPE Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | RAT antibody to MOUSE F4/80:RPE (Antibody to) |
| Alternative technique | antibodies |
| Identity | 10293 |
| Gene | RPE |
| Long gene name | ribulose-5-phosphate-3-epimerase |
| Locus | 2q34 |
| Discovery year | 2001-06-22 |
| Entrez gene record | 6120 |
| RefSeq identity | NM_006916 |
| Havana BLAST/BLAT | OTTHUMG00000154690 |