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RAT ANTI MOUSE PLVAP:Biotin Antibody

RAT ANTI MOUSE PLVAP:Biotin Antibody size: 100ug 271

Supplier MBS MONO
Price 271
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asPLVAP
Other names MECA-32 antigen, MECA-32 antigen, Plasmalemma vesicle protein 1, Plasmalemma vesicle-associated protein, plasmalemma vesicle associated protein, plasmalemma vesicle protein 1, plasmalemma vesicle-associated protein, plasmalemma vesicle-associated protein
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene namePLVAP
Gene name synonimsN/A
Other gene names MECA32, PV-1, Plvap, Pv1, Pv1, Plvap
ClonalityMonoclonal
Immunoglobulin isotypeIgG2a
CloneMECA-32
Host organismRat (Rattus norvegicus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus)
Specificity and cross-reactivity In adult and embryonic mice, In embryonic mice, PLVAP expression, PLVAP is a transmembrane homodimer which is associated with endothelial cell caveolae and fenestrae, PLVAP is primarily expressed on endothelial tissues but shows restricted distribution in the skeletal, PLVAP is selectively up-regulated in a variety of high-grade brain tumors, PLVAP represents a novel marker of brain tumour angiogenesis and integrity of the blood-brain barrier and is a potential therapeutic target, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_In humans, a 60kD protein which is otherwise known as MECA-32 and PV-1, as well as other cerebral disorders associated with blood-brain barrier disruption, cardiac and brain tissues, including glioblastoma and metastatic carcinoma, on the vasculature associated with blood brain barrier has been reported to be developmentally regulated, such as acute ischemia, PLVAP This item recognises murine plasmalemma vesicle-associated protein (PLVAP)
Purification methodN/A
Form/AppearanceBiotin (Purified IgG conjugated to Biotin - liquid)
Concentration1 miligram per 1 mililiter, IgG concentration 0
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: Immunohistology - Frozen (IHC), Flow Cytometry (FACS)
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
ConjugationBiotinylated
Gene targetPLVAP:
Short nameRAT ANTI MOUSE PLVAP: Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelBiotin
Alternative nameRAT antibody to MOUSE PLVAP:biotinilated (Antibody to)
Alternative techniqueantibodies
Identity 13635
Gene PLVAP
Long gene name plasmalemma vesicle associated protein
Synonyms gp68 PV-1 PV1 FELS
Synonyms name PV-1 protein , fenestrated-endothelial linked structure protein
Locus 19p13, 11
Discovery year 2001-04-27
GenBank acession AF326591
Entrez gene record 83483
Pubmed identfication 11401446
RefSeq identity NM_031310
Havana BLAST/BLAT OTTHUMG00000182784

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